ArticlePloS one2022
Point-prevalence survey of antibiotic use at three public referral hospitals in Kenya.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Surveillance of antimicrobial utilization in Africa: a systematic review and meta-analysis of prescription rates, indications, and quality of use from point prevalence surveys.Antimicrobial resistance and infection control · 2024Pooled it
- Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Antibiotic Use Among Hospitalized Patients in Africa: A Systematic Review of Point Prevalence Studies.Journal of racial and ethnic health disparities · 2024Pooled it
- National and Hospital Level Antimicrobial Consumption Patterns in Kenya.Antibiotics (Basel, Switzerland) · 2026Article
- High gastrointestinal carriage rates of extended-spectrum-β-lactamase-producing enterobacterales and associated factors among hospitalized and nonhospitalized children in Kenya.Scientific reports · 2026Article
- Burden of Antibiotic Resistance in Hospitalized Children in Kenya: Associations with Mortality, Hospital Stay, and Treatment Costs.The American journal of tropical medicine and hygiene · 2026Article
- A multicenter point-prevalence survey of antibiotic utilization patterns in Ethiopia: implications for strengthening stewardship programs.BMC infectious diseases · 2026Article
- Adherence to national pediatric antibiotic prescription guideline for pneumonia treatment of children 2-59 months: a retrospective chart review at a regional hospital in Rwanda.BMC infectious diseases · 2025Article
- Antibiotic susceptibility patterns of clinical isolates of salmonella species producing extended spectrum beta lactamases as predictor of multidrug resistance in a tertiary hospital, Southeastern Nigeria.BMC infectious diseases · 2025Article
- Patterns of antimicrobial use in Qatar's hospitals: Results from the first national point prevalence survey.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025Article
- Antimicrobial Use at a Tertiary-Care Hospital in Türkiye According to the WHO Access, Watch and Reserve (AWaRe) Classification: A Point Prevalence Survey.Infectious diseases & clinical microbiology · 2025Article
- Diagnostic Underuse and Antimicrobial Resistance Patterns Among Hospitalized Children in a National Referral Hospital in Kenya: A Five-Year Retrospective Study.Antibiotics (Basel, Switzerland) · 2025Article
- Current status and future direction of antimicrobial stewardship programs and antibiotic prescribing in primary care hospitals in Zambia.JAC-antimicrobial resistance · 2025Article
- Antibiotic use at the Centre Hospitalier Universitaire de Zone d'Abomey Calavi/Sô-Ava (CHUZ/AS) in Benin: a point prevalence survey.JAC-antimicrobial resistance · 2025Article
- Antimicrobial stewardship challenges at a referral Hospital in Western Kenya: insights from a Kakamega-Cambridge health partnership.Frontiers in public health · 2025Article
- Point Prevalence Survey of Antibiotic Use in Level 1 hospitals in Zambia: Future Prospects for Antimicrobial Stewardship Programs.Infection and drug resistance · 2025Article
- Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- WHO-Point prevalence survey of antibiotic use in a Senegalese tertiary care hospital.PLOS global public health · 2025Article
- A Point Prevalence Survey of antibiotics use patterns at Tanga Regional Referral Hospital in Tanzania.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Surveillance of antibiotics use in inpatients at Benjamin Mkapa Zonal Referral Hospital in Dodoma, Tanzania: a point prevalence survey.BMJ open · 2024Article
Corrections and comments
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Authors and funding
21 authors at 9 institutions in 2 countries.
Funding
Abstract
Antimicrobial stewardship encourages appropriate antibiotic use, the specific activities of which will vary by institutional context. We investigated regional variation in antibiotic use by surveying three regional public hospitals in Kenya. Hospital-level data for antimicrobial stewardship activities, infection prevention and control, and laboratory diagnostic capacities were collected from hospital administrators, heads of infection prevention and control units, and laboratory directors, respectively. Patient-level antibiotic use data were abstracted from medical records using a modified World Health Organization point-prevalence survey form. Altogether, 1,071 consenting patients were surveyed at Kenyatta National Hospital (KNH, n = 579), Coast Provincial General Hospital (CPGH, n = 229) and Moi Teaching and Referral Hospital (MTRH, n = 263). The majority (67%, 722/1071) were ≥18 years and 53% (563/1071) were female. Forty-six percent (46%, 489/1071) were receiving at least one antibiotic. Antibiotic use was higher among children <5 years (70%, 150/224) than among other age groups (40%, 339/847; P < 0.001). Critical care (82%, 14/17 patients) and pediatric wards (59%, 155/265) had the highest proportion of antibiotic users. Amoxicillin/clavulanate was the most frequently used antibiotic at KNH (17%, 64/383 antibiotic doses), and ceftriaxone was most used at CPGH (29%, 55/189) and MTRH (31%, 57/184). Forty-three percent (326/756) of all antibiotic prescriptions had at least one missed dose recorded. Forty-six percent (204/489) of patients on antibiotics had a specific infectious disease diagnosis, of which 18% (37/204) had soft-tissue infections, 17% (35/204) had clinical sepsis, 15% (31/204) had pneumonia, 13% (27/204) had central nervous system infections and 10% (20/204) had obstetric or gynecological infections. Of these, 27% (56/204) had bacterial culture tests ordered, with culture results available for 68% (38/56) of tests. Missed antibiotic doses, low use of specimen cultures to guide therapy, high rates of antibiotic use, particularly in the pediatric and surgical population, and preference for broad-spectrum antibiotics suggest antibiotic use in these tertiary care hospitals is not optimal. Antimicrobial stewardship programs, policies, and guidelines should be tailored to address these areas.
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