Evidence map›Paper›PMID 35709211›Full record

ArticlePloS one2022

Evidence-based service delivery interventions for testing, linking, treating, and retaining children and adolescents living with HIV in primary health care settings: Protocol for a systematic review.

Nande Putta, Caitlin E Hansen, Melissa C Funaro, Melissa Campbell, Shaffiq Essajee, Dorothy Mbori-Ngacha, Shadrack Frimpong, Shi-Yi Wang, Elijah Paintsil

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nande PuttaUnited Nations Children's Fund (UNICEF), Health Programme, New York, New York, United States of America.
Caitlin E HansenDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, United States of America.
Melissa C FunaroHarvey Cushing/John Hay Whitney Medical Library, Yale School of Medicine, New Haven, Connecticut, United States of America.
Melissa CampbellDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, United States of America.
Shaffiq EssajeeUnited Nations Children's Fund (UNICEF), Health Programme, New York, New York, United States of America.
Dorothy Mbori-NgachaUnited Nations Children's Fund (UNICEF), Health Programme, New York, New York, United States of America.
Shadrack FrimpongDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, United States of America.
Shi-Yi WangYale School of Public Health, New Haven, Connecticut, United States of America.ORCID 0000-0002-3294-5784
Elijah PaintsilDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, United States of America.ORCID 0000-0002-8283-4564

Funding

Pediatric HIV Disclosure Intervention and Benefits Study-(PH-DIBS)R01HD103512 · NICHD · YALE UNIVERSITY · PI PAINTSIL, ELIJAH, REYNOLDS, NANCY R · 2020 to 2024
$3.4M
HIV Co-morbidities Research Training in Ghana (HIV-ComRT)D43TW011526 · FIC · YALE UNIVERSITY · PI PAINTSIL, ELIJAH · 2020 to 2024
$1.5M
An mHealth Approach to Increasing Adolescent Vaccine UptakeK23HD098710 · NICHD · YALE UNIVERSITY · PI HANSEN, CAITLIN · 2019 to 2021
$361k
FIC NIH HHS D43 TW011526NICHD NIH HHS K23 HD098710NICHD NIH HHS R01 HD103512
6 · The paper itself

Abstract

backgroundAt the end of 2019, there were about 2.8 million children and adolescents aged 0-19 living with HIV. In contrast to pregnant women and adults, service delivery for children and adolescents living with HIV continues to lag behind with regard to access to care, components of care delivery, treatment options, and clinical and immunologic outcomes.

aimThe aim of this systematic review is to synthesize the evidence on the most effective interventions, models, programs, and strategies to optimize the delivery of services for the testing, linkage, treatment and retention of children and adolescents living with HIV globally.

methodsThis review protocol is registered at PROSPERO with Registration number: CRD42020209553. The systematic review will be conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P). We will use a comprehensive search strategy to search several bibliographic databases including MEDLINE, Embase, CINAHL, Cochrane Library, Global Health, and Psycinfo to identify relevant studies published in the last ten years (2010 to 2020). In addition, we will review cited and citing references of included studies. A pair of reviewers will independently screen titles, abstracts and full texts of articles, extract data from articles meeting inclusion criteria and perform quality assessments of the evidence collected. We will conduct a narrative synthesis of our findings, and if there are sufficient clinically similar studies available, we will conduct meta-analysis using a random-effects model. DISCUSSION: This review will provide evidence on service delivery models that have been evaluated in a range of settings to efficiently and effectively locate, link, treat and retain in care, children and adolescents living with HIV. The synthesized evidence will help guide national governments and health care providers in prioritizing and adopting evidence-based service delivery approaches for children and adolescents living with HIV. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020209553.

Indexed as

Delivery of Health CareHIV InfectionsAdolescentChildFemaleHumansMeta-Analysis as TopicPregnancyPrimary Health CareReview Literature as TopicSystematic Reviews as Topic

Identifiers

PMID35709211
PMCPMC9202933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.