Evidence map›Paper›PMID 35709090›Full record

Observational studyPloS one2022

Evaluation of a mobile application tool (BiliNorm) to improve care for newborns with hyperbilirubinemia in Indonesia.

Mahendra T A Sampurna, Kinanti A Ratnasari, Zahra S Irawan, Risa Etika, Martono T Utomo, Brigitta I R V Corebima, Pieter J J Sauer, Arend F Bos, Christian V Hulzebos, Peter H Dijk

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mahendra T A SampurnaDepartment of Pediatrics, Faculty of Medicine Universitas Airlangga, Airlangga Teaching Hospital, Surabaya, Indonesia.ORCID 0000-0002-7529-8142
Kinanti A RatnasariDepartment of Pediatrics, Faculty of Medicine Universitas Airlangga, Dr Soetomo General Hospital, Surabaya, Indonesia.
Zahra S IrawanDepartment of Pediatrics, Faculty of Medicine Universitas Airlangga, Dr Soetomo General Hospital, Surabaya, Indonesia.
Risa EtikaDepartment of Pediatrics, Faculty of Medicine Universitas Airlangga, Dr Soetomo General Hospital, Surabaya, Indonesia.
Martono T UtomoDepartment of Pediatrics, Faculty of Medicine Universitas Airlangga, Dr Soetomo General Hospital, Surabaya, Indonesia.
Brigitta I R V CorebimaDepartment of Pediatrics, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, Indonesia.
Pieter J J SauerDepartment of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.
Arend F BosDepartment of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.
Christian V HulzebosDepartment of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0002-8159-7501
Peter H DijkDepartment of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.
Airlangga University · IDUniversity Medical Center Groningen · NLUniversity of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere hyperbilirubinemia is more frequent in low- and middle-income countries such as Indonesia than in high-income countries. One of the contributing factors might be the lack of adherence to existing guidelines on the diagnosis and treatment of hyperbilirubinemia. We developed a new national guideline for hyperbilirubinemia management in Indonesia. To help healthcare workers use this guideline, a web-based decision support tool application may improve both the adherence to the guideline and the care for infants with hyperbilirubinemia.

methodsWe developed a web-based application (BiliNorm) to be used on a smartphone that displays the bilirubin level of the patient on the nomogram and advises about the treatment that should be started. Healthcare workers of two teaching hospitals in East Java, Indonesia, were trained on the use of BiliNorm. At 6 months after the introduction, a questionnaire was sent to those who worked with the application enquiring about their experiences. An observational study was conducted in two time epochs. A chart review of infants with hyperbilirubinemia in the two hospitals was sent. The appropriateness of hyperbilirubinemia management during a 6-month period before BiliNorm introduction was compared to that during a 7-month period after its introduction.

resultsA total of 43 participants filled in the questionnaire, the majority (72%) of them indicated that BiliNorm was well received and easy to use. Moreover, 84% indicated that BiliNorm was helpful for the decision to start phototherapy. Chart review of 255 infants before BiliNorm introduction and that of 181 infants after its introduction indicated that significantly more infants had received treatment according to the guideline (38% vs 51%, p = 0.006). Few infants received phototherapy, but bilirubin level was not measured (14% vs 7%, p = 0.024). There was no difference in the proportion of infants who were over- and under-treated (34% vs 32% and 14% vs 10%, respectively).

conclusionsThe web-based decision tool BiliNorm appears to be a valuable application. It is easy to use for healthcare workers and helps them adhere to the guideline. It improves the care for infants with hyperbilirubinemia and may help reduce the incidence of severe hyperbilirubinemia in Indonesia.

Indexed as

Hematologic DiseasesHyperbilirubinemia, NeonatalMobile ApplicationsBilirubinHumansHyperbilirubinemiaIndonesiaInfant, NewbornPhototherapyBilirubin

Identifiers

PMID35709090
PMCPMC9202860
OpenAlexW4282965439

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.