Evidence map›Paper›PMID 35708836›Full record

ArticleInternational journal of colorectal disease2022

Local recurrence of robot-assisted total mesorectal excision: a multicentre cohort study evaluating the initial cases.

T A Burghgraef, R M P H Crolla, M Fahim, G P van der Schelling, A B Smits, L P S Stassen, J Melenhorst, P M Verheijen, E C J Consten

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

T A BurghgraefDepartment of Surgery, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands. t.a.burghgraef@umcg.nl.ORCID http://orcid.org/0000-0001-8781-9630
R M P H CrollaDepartment of Surgery, Amphia Hospital, Breda, the Netherlands.
M FahimDepartment of Surgery, St Antonius Hospital, Nieuwegein, the Netherlands.
G P van der SchellingDepartment of Surgery, Amphia Hospital, Breda, the Netherlands.
A B SmitsDepartment of Surgery, St Antonius Hospital, Nieuwegein, the Netherlands.
L P S StassenDepartment of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
J MelenhorstDepartment of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
P M VerheijenDepartment of Surgery, Meander Medical Centre, Maatweg 3, 3813 TZ, Amersfoort, the Netherlands.
E C J ConstenDepartment of Surgery, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.
Amphia Ziekenhuis · NLMaastricht University Medical Centre · NLSt. Antonius Ziekenhuis · NLUniversity Medical Center Groningen · NLMeander Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvidence regarding local recurrence rates in the initial cases after implementation of robot-assisted total mesorectal excision is limited. This study aims to describe local recurrence rates in four large Dutch centres during their initial cases.

methodsFour large Dutch centres started with the implementation of robot-assisted total mesorectal excision in respectively 2011, 2012, 2015, and 2016. Patients who underwent robot-assisted total mesorectal excision with curative intent in an elective setting for rectal carcinoma defined according to the sigmoid take-off were included. Overall survival, disease-free survival, systemic recurrence, and local recurrence were assessed at 3 years postoperatively. Subsequently, outcomes between the initial 10 cases, cases 11-40, and the subsequent cases per surgeon were compared using Cox regression analysis.

resultsIn total, 531 patients were included. Median follow-up time was 32 months (IQR: 19-50]. During the initial 10 cases, overall survival was 89.5%, disease-free survival was 73.1%, and local recurrence was 4.9%. During cases 11-40, this was 87.7%, 74.1%, and 6.6% respectively. Multivariable Cox regression did not reveal differences in local recurrence between the different case groups.

conclusionLocal recurrence rate during the initial phases of implantation of robot-assisted total mesorectal procedures is low. Implementation of the robot-assisted technique can safely be performed, without additional cases of local recurrence during the initial cases, if performed by surgeons experienced in laparoscopic rectal cancer surgery.

Indexed as

LaparoscopyRectal NeoplasmsRoboticsCohort StudiesDisease-Free SurvivalHumansNeoplasm Recurrence, LocalTreatment OutcomeLocal recurrenceRectal cancerRobot-assisted surgeryTotal mesorectal excision

Identifiers

PMID35708836
PMCPMC9262776
OpenAlexW4283009209

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.