Evidence map›Paper›PMID 35708459›Full record

Observational studyJournal of dental research2022

Chronic Pain-Related Jaw Muscle Motor Load and Sensory Processing.

J C Nickel, Y M Gonzalez, Y Wu, Y Liu, H Liu, L R Iwasaki

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

J C NickelDepartment of Orthodontics, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
Y M GonzalezDepartment of Oral Diagnostic Sciences, School of Dental Medicine, University at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-5294-4287
Y WuDepartment of Integrative Biomedical and Diagnostic Sciences, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
Y LiuDepartment of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN, USA.
H LiuDepartment of Orthodontics, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
L R IwasakiDepartment of Orthodontics, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USEast Tennessee State University · USUniversity at Buffalo, State University of New York · US

Funding

Joules, Genes, and Behaviors: a multifactorial assessment of TMD risk indicatorsR01DE016417 · NIDCR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI NICKEL, JEFFREY C · 2006 to 2015
$4.4M
NIDCR NIH HHS R01 DE016417
6 · The paper itself

Abstract

Chronic pain associated with temporomandibular disorders (TMDs) may reflect muscle mechanoreceptor afferent barrage and dysregulated sensory processing. This observational study tested for associations between Characteristic Pain Intensity (CPI), physical symptoms (Patient Health Questionnaire-15 [PHQ-15]), and cumulative jaw muscle motor load (mV*s). In accordance with institutional review board oversight and Strengthening the Reporting of Observational Studies in Epidemiology guidelines, adult subjects gave informed consent and were identified via Diagnostic Criteria for TMD (DC-TMD) examination and research protocols. Subjects were assigned to ±Pain groups using DC-TMD criteria for myalgia. CPI scores characterized pain intensity. PHQ-15 scores were surrogate measures of dysregulated sensory processing. Laboratory tests were performed to quantify masseter and temporalis muscle activities (mV) per bite force (N) for each subject. In their natural environments, subjects recorded day- and nighttime electromyography from which cumulative jaw muscle motor loads (mV*s) were determined for activities consistent with bite forces of >1 to ≤2 and >2 to ≤5 N. Data were assessed using univariate analysis of variance, simple effects tests, K-means cluster classification, and 3-dimensional regression analyses. Of 242 individuals screened, 144 enrolled, and 125 with complete data from study protocols, there were 35 females and 15 males for +Pain and 35 females and 40 males for -Pain. Subjects produced 324 daytime and 341 nighttime recordings of average duration 6.9 ± 1.7 and 7.6 ± 1.7 h, respectively. Overall, +Pain compared to -Pain subjects had significantly higher (all

Indexed as

Chronic PainMyalgiaAdultElectromyographyFemaleHumansMaleMasseter MusclePerceptionTemporal Muscleelectromyographymasticatory musclesmyalgiasensory thresholdssomatosensory disorderstemporomandibular joint disorders

Identifiers

PMID35708459
PMCPMC9403723
OpenAlexW4282979345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.