ArticleExpert review of gastroenterology & hepatology2022
The clinical implication of psychiatric illnesses in patients with alcoholic liver disease: an analysis of US hospitals.
Article in Expert review of gastroenterology & hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Mental health service users' pre- and post-therapy hospitalization rates: A data linkage study.The British journal of clinical psychology · 2026Article
- The prognostic impact of psychiatric intervention on alcohol-associated liver disease: The UK Biobank cohort study.Clinical and molecular hepatology · 2024Article
- Antidepressants in People With Chronic Liver Disease and Depression: When Are They Warranted and How to Choose the Suitable One?Journal of clinical and experimental hepatologyReview
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10 authors.
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Abstract
backgroundIn this study, we evaluate the clinical impact of psychiatric illnesses (PI) on the hospital outcomes of patients admitted with alcoholic liver disease (ALD).
methodsFrom the National Inpatient Sample from 2012-2017, patients with alcoholic cirrhosis or alcoholic hepatitis were selected and stratified using the presence/absence of PI (which was a composite of psychiatric conditions). The cases were propensity score-matched to PI-absent controls and were compared to the following endpoints: mortality, death due to suicide, length of stay (LOS), hospitalization charges, and hepatic complications.
resultsAfter matching, there were 122,907 PI with and 122,907 without PI. Those with PI were younger (51.8 vs. 51.9 years p = 0.02) and more likely to be female (39.2 vs. 38.7% p = 0.01); however, there was no difference in race. Patients with PI had lower rates of alcoholic cirrhosis but higher rates of alcoholic hepatitis/alcoholic hepatic steatosis. In multivariate, patients with PI had lower rates of all-cause mortality (aOR 0.51 95%CI 0.49-0.54); however, they experienced higher rates of deaths due to suicide (aOR 3.00 95%CI 1.56-5.78) and had longer LOS (aOR 1.02 95%CI 1.01-1.02).
conclusionPresence of PI in ALD patients is associated with prolonged hospital stay and higher rates deaths due to suicide.
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