Evidence map›Paper›PMID 35708275›Full record

ArticleACS biomaterials science & engineering2022

Versatile-in-All-Trades: Multifunctional Boron-Doped Calcium-Deficient Hydroxyapatite Directs Immunomodulation and Regeneration.

Ahmet Engin Pazarçeviren, Sema Akbaba, Zafer Evis, Ayşen Tezcaner

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ahmet Engin PazarçevirenDepartment of Engineering Sciences, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0001-5233-860X
Sema AkbabaDepartment of Biotechnology, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0002-6063-078X
Zafer EvisDepartment of Engineering Sciences, Middle East Technical University, Ankara 06800, Turkey.
Ayşen TezcanerDepartment of Engineering Sciences, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0003-4292-5856
Middle East Technical University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osseointegration of implants depends on several intertwined factors: osteogenesis, angiogenesis, and immunomodulation. Lately, novel reinforcements allowing faster bonding with osseous tissue have been explored intensively. In this study, we hypothesized the use of boron as a major multifunctional ion to confer versatility to calcium-deficient hydroxyapatite (cHA) synthesized by a wet precipitation/microwave reflux method. By synthesis of boron-doped calcium-deficient hydroxyapatite (BcHA), we expected to obtain an osteoimmunomodulatory and regenerative nanoreinforcement. BcHA was found to possess a pure HA phase, a greater surface area (66.41 m

Indexed as

BoronDurapatiteCalciumCell ProliferationHumansHuman Umbilical Vein Endothelial CellsImmunomodulationVascular Endothelial Growth Factor ABoronCalciumDurapatiteVascular Endothelial Growth Factor Aangiogenesisboronhydroxyapatite/tricalcium phosphateimmunomodulationosteogenesis

Identifiers

PMID35708275
PMCPMC9277590
OpenAlexW4282976339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.