ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2022
Influence of eye tilt on corneal densitometry.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Influence of Room Illumination on Corneal Densitometry.Translational vision science & technology · 2026Article
- Development of risk prediction model for small incision lenticule extraction.Frontiers in medicine · 2025Article
- Investigation of How Corneal Densitometry Artefacts Affect the Imaging of Normal and Keratoconic Corneas.Bioengineering (Basel, Switzerland) · 2024Article
- The Impact of Standard Cross-Linking on the Corneal Optical Density-Age Relationship in Keratoconus After Mechanical Stripping of the Epithelium.Journal of ophthalmology · 2024Article
- OCT based corneal densitometry: the confounding effect of epithelial speckle.Biomedical optics express · 2023Article
- Influence of eye tilt on corneal densitometry.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate whether Pentacam densitometry readings are affected by corneal tilt.
methodsIn a prospective study, the right eyes of 86 healthy participants aged 42.8 ± 20.0 years (range 18-79 years) were imaged using Scheimpflug tomography. Elevation maps were exported to calculate corneal tilt using custom-made software, and densitometry readings were acquired directly from the corneal densitometry analysis add-on to the standard software Oculus Pentacam HR. Simple mediation analysis was applied to study age as a confounding factor in the correlation between corneal tilt and corneal densitometry.
resultsCorneal tilt and corneal densitometry are not independent from one another because age is significantly correlated with both corneal tilt (r = 0.50, p < 0.001) and corneal densitometry (r = 0.91, p < 0.001). Only 3.8% of the correlation between tilt and densitometry operates directly, while the remaining 96.2% depends on age.
conclusionsCorneal tilt plays a role in corneal densitometry readings, even though the interaction is strongly influenced by age. Age is a well-known factor in densitometry readings that should be taken into consideration when interpreting Scheimpflug densitometry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.