Evidence map›Paper›PMID 35708115›Full record

Observational studyActa paediatrica (Oslo, Norway : 1992)2022

Trends in ferritin measurements in children and adolescents: A Finnish 9-year observational study.

Atte Nikkilä, Olli Lohi, Niina Nieminen, Péter Csonka

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Atte NikkiläTampere Center for Child, Adolescent and Maternal Health Research, Tampere University, Tampere, Finland.ORCID 0000-0003-0292-2386
Olli LohiTampere Center for Child, Adolescent and Maternal Health Research, Tampere University, Tampere, Finland.ORCID 0000-0001-9195-0797
Niina NieminenTerveystalo Healthcare, Helsinki, Finland.
Péter CsonkaTampere Center for Child, Adolescent and Maternal Health Research, Tampere University, Tampere, Finland.ORCID 0000-0003-0819-7875
Tampere University · FIEtelä-Karjalan sosiaali ja terveyspiiri · FI

Funding

Lasten Syöpäsäätiö Väre (Paediatric Cancer Foundation Väre)
6 · The paper itself

Abstract

aimA lack of stored iron, indicated by low serum ferritin, has been associated with various clinical symptoms. There are no longitudinal data on the frequency of ferritin measurements in children and adolescents.

methodsA total of 2834 children aged <18 years with serum ferritin and other anaemia-related blood parameters taken during an outpatient visit between 2012 and 2019 were investigated. Patients with acute infections were excluded. Nationwide temporal and regional variations and correlations with public information searches through Google were analysed.

resultsA significant increase in the frequency of ferritin measurements was seen starting in 2018, with a 47-fold rise in 2019 compared to 2012. A simultaneous escalation in Google Search activity was seen. Deficiency of stored iron was relatively common: 21.6% of children with normal haemoglobin and 14.9% of non-anaemic children with normal red cell indices exhibited ferritin levels below 15 μg/L.

conclusionFerritin measurement has increased greatly among children and adolescents. Our results suggest that public interest and popular trends can significantly influence health care practices. This calls for further investigation into the causes and consequences of such a phenomenon. Prospective randomised intervention studies are needed to evaluate the utility of iron supplementation in patients with low iron storage levels.

Indexed as

AnemiaAnemia, Iron-DeficiencyAdolescentChildFerritinsFinlandHemoglobinsHumansIronProspective StudiesFerritinsHemoglobinsIronanaemiahealth seekingiron deficiencypublic healthserum ferritinsocial mediatrends

Identifiers

PMID35708115
PMCPMC9541652
OpenAlexW4282970788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.