ArticleJournal of feline medicine and surgery2022
Investigated regional apparent diffusion coefficient values of the morphologically normal feline brain.
Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Morphologic characteristics of distal intracranial arteries in relation to structural changes in the brain after chronic alcohol consumption.Scientific reports · 2025Article
- Distinguishing Laterality in Brain Injury in Rabbit Fetal Magnetic Resonance Imaging Using Novel Volume Rendering Techniques.Developmental neuroscience · 2025Article
- Regional ADC values of the morphologically normal canine brain.Frontiers in veterinary science · 2023Article
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3 authors at 1 institution in 1 country.
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Abstract
objectivesDiffusion-weighted imaging (DWI) MRI is increasingly available in veterinary medicine for investigation of the brain. However, apparent diffusion coefficient (ADC) values have only been reported in a small number of cats or in research settings. The aim of this study was to investigate the ADC values of different anatomical regions of the morphologically normal brain in a feline patient population. Additionally, we aimed to assess the possible influence on the ADC values of different patient-related factors, such as sex, body weight, age, imaging of the left and right side of the cerebral hemispheres and white vs grey matter regions.
methodsThis retrospective study included cats undergoing an MRI (3T) examination with DWI sequences of the head at the Vetsuisse Faculty of the University Zurich between 2015 and 2021. Only cats with morphologically normal brains were included. On the ADC maps, 10 regions of interest (ROIs) were manually drawn on the following anatomical regions: caudate nucleus; internal capsule (two locations); piriform lobe; thalamus; hippocampus; cortex cerebri (two locations); cerebellar hemisphere; and one ROI in the centre of the cerebellar vermis. Except for the ROI at the cerebellar vermis, each ROI was drawn in the left and right hemisphere. The ADC values were calculated by the software and recorded.
resultsA total of 129 cats were included in this study. The ADC varied in the different ROIs, with the highest mean ADC value in the hippocampus and the lowest in the cerebellar hemisphere. ADC was significantly lower in the white cerebral matter compared with the grey matter. ADC values were not influenced by age, with the exception of the hippocampus and the cingulate gyrus. CONCLUSION AND RELEVANCE: ADC values of different anatomical regions of the morphologically normal feline brain in a patient population of 129 cats in a clinical setting are reported for the first time.
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