Evidence map›Paper›PMID 35707851›Full record

ArticleBioengineered2022

Toll-like receptor 9 (TLR9) gene deletion-mediated fracture healing in type II diabetic osteoporosis associates with inhibition of the nuclear factor-kappa B (NF-κB) signaling pathway.

Jiakai Han, Qian Zheng, Yongxia Cheng, Yong Liu, Yuxin Bai, Bin Yan, Sufen Guo, Jianbo Yu, Xinxin Li, Chong Wang

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Review
  5. Biology · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jiakai HanEndocrinology Department, Huaihe Hospital of Henan University, Kaifeng, PR, China.
Qian ZhengEndocrinology Department, Yan'an Hospital of Kunming Medical University, Kunming, PR, China.
Yongxia ChengPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.
Yong LiuPlatform Management Division, Scientific Research Division of Mudanjiang Medical College, Mudanjiang, PR, China.
Yuxin BaiPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.
Bin YanPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.
Sufen GuoPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.
Jianbo YuPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.
Xinxin LiUltrasound Department, Second Hospital of Mudanjiang Medical College, Mudanjiang, PR, China.
Chong WangPathology Diagnosis Center, The HongQi Hospital, The First Clinical Medical School of Mudanjiang Medical College, Mudanjiang, PR, China.ORCID 0000-0002-7408-3545
Mudanjiang Medical University · CNHenan University Huaihe Hospital and Huaihe Clinical Institute · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is characterized by increased fracture risk. Evidence from

Indexed as

Diabetes Mellitus, Type 2OsteoporosisToll-Like Receptor 9AnimalsFracture HealingGene DeletionMiceNF-kappa BSignal TransductionTumor Necrosis Factor-alphaNF-kappa BTlr9 protein, mouseToll-Like Receptor 9Tumor Necrosis Factor-alphafracture healingNF-κB signaling pathwayTLR9 knockouttype II diabetic osteoporosis

Identifiers

PMID35707851
PMCPMC9275877
OpenAlexW4283010108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.