Evidence map›Paper›PMID 35707463›Full record

ArticleFrontiers in endocrinology2022

Therapeutic Potential of Targeting Periostin in the Treatment of Graves' Orbitopathy.

Sun Young Jang, Jinjoo Kim, Jung Tak Park, Catherine Y Liu, Bobby S Korn, Don O Kikkawa, Eun Jig Lee, Jin Sook Yoon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sun Young JangDepartment of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, South Korea.
Jinjoo KimDepartment of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
Jung Tak ParkDepartment of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, South Korea.
Catherine Y LiuDivision of Oculofacial Plastic and Reconstructive Surgery, University of California, San Diego, La Jolla, CA, United States.
Bobby S KornDivision of Oculofacial Plastic and Reconstructive Surgery, University of California, San Diego, La Jolla, CA, United States.
Don O KikkawaDivision of Oculofacial Plastic and Reconstructive Surgery, University of California, San Diego, La Jolla, CA, United States.
Eun Jig LeeDivision of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Jin Sook YoonDepartment of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
University of California San Diego · USSeverance Hospital · KRYonsei University · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periostin is a matricellular protein that is ubiquitously expressed in normal human tissues and is involved in pathologic mechanism of chronic inflammatory and fibrotic disease. In this study we investigate periostin in the pathogenesis of Graves' orbitopathy (GO) using human orbital adipose tissue obtained from surgery and primary cultured orbital fibroblasts

Indexed as

Graves OphthalmopathyAdipogenesisCytokinesFibroblastsFibrosisHumansInflammationRNA, Small InterferingCytokinesRNA, Small InterferingadipogenesisfibroblastsfibrosisGraves orbitopathyinflammationperiostin

Identifiers

PMID35707463
PMCPMC9189304
OpenAlexW4281993263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.