ArticleFrontiers in oncology2022
The Preoperative Diagnostic Performance of Multi-Parametric Quantitative Assessment in Rectal Carcinoma: A Preliminary Study Using Synthetic Magnetic Resonance Imaging.
Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 9 citations in OpenAlex.
- Metabolic Dysfunction-associated Steatotic Liver Disease Diminishes the Efficacy of miR-125b-5p-engineered MSC Therapy for Hepatocellular Carcinoma via HK2 Upregulation: A Multimodal Theranostic Study.Journal of clinical and translational hepatology · 2026Article
- Multiparametric magnetic resonance imaging (MRI) integrating amide proton transfer-weighted (APTw) imaging, synthetic MRI, and multiplexed sensitivity encoding diffusion-weighted imaging (MUSE DWI) in the diagnosis and grading of prostate cancer.Quantitative imaging in medicine and surgery · 2026Article
- MRI T1 relaxation time for evaluating early complete response to neoadjuvant treatment in rectal cancer: measurement at six weeks - a protocol article.Acta radiologica open · 2025Article
- Technical aspects and clinical applications of synthetic MRI: a scoping review.Diagnosis (Berlin, Germany) · 2025Article
- Synthetic double inversion recovery imaging for rectal cancer T staging evaluation: imaging quality and added value to T2-weighted imaging.Insights into imaging · 2024Article
- Synthetic MRI and amide proton transfer-weighted MRI for differentiating between benign and malignant sinonasal lesions.European radiology · 2024Article
- Multiparametric approach with synthetic MR imaging for diagnosing salivary gland lesions.Japanese journal of radiology · 2024Article
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6 authors at 1 institution in 1 country.
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Abstract
Objective: Synthetic MRI (SyMRI) can reconstruct different contrast-weighted images(T1, T2, PD) and has shorter scan time, easier post-processing and better reproducibility. Some studies have shown splendid correlation with conventional mapping techniques and no degradation in the quality of syMRI images compared with conventional MRI. It is crucial to select an individualized treatment plan based on the preoperative images of rectal carcinoma (RC). We tried to explore the feasibility of syMRI on T, N stage and extramural vascular invasion (EMVI) of rectal cancer. Materials and Methods: A total of 100 patients (37 females and 63 males) diagnosed with rectal carcinoma were enrolled. All the patients underwent preoperative pelvic MR examinations including conventional MR sequence and synthetic MRI. Two radiologists evaluated the MRI findings of each rectal carcinoma and EMVI score in consensus. The values for T1, T2 relaxation times and PD value were measured in tumor(ROI-1) and pararectal fat space(ROI-2) and analyzed independently. A receiver operating characteristic (ROC) analysis was performed. Correlations between the T1, T2 and PD values and EMVI score were also evaluated. Results: Compared with the normal rectal wall, the values of T1 and T2 relaxation times of the tumor were significantly higher ( Conclusion: Synthetic MRI can provide multi-parameter quantitative image maps with a easier measurement and slightly shorter acquisition time compared with conventional MRI. The measurement of multi-parametric quantitative values contributes to diagnosing the tumor and evaluating T stage, N stage and EMVI. It has the potential to be used as a preoperative diagnostic and grading technique in rectal carcinoma.
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