Evidence map›Paper›PMID 35707316›Full record

ArticleInternational journal of breast cancer2022

The Effect of a Combined Modified Pectoral and Stellate Ganglion Block on Stress and Inflammatory Response in Patients Undergoing Modified Radical Mastectomy.

Jun Geng, Jing Wang, Yaowen Zhang, Wenxiang Song, Junjia Zhu, Jianqing Chen, Zhen Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of breast cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jun GengDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0002-7309-8446
Jing WangDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0003-0138-0749
Yaowen ZhangDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0001-5549-021X
Wenxiang SongDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0002-1100-3149
Junjia ZhuDepartment of General Surgery, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0002-5809-9897
Jianqing ChenDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0002-4902-9061
Zhen WuDepartment of Anesthesiology, Jiangyin Hospital Affiliated to Southeast University Medical School, Wuxi, 214400 Jiangsu, China.ORCID https://orcid.org/0000-0002-1128-9132
Jiangyin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Regional anaesthesia reports to attenuate stress and inflammatory responses associated with surgical resection; however, the effectiveness of combined nerve blocks is less often investigated. We evaluated whether a combination of a pectoral nerve block (PNB) and stellate ganglion block (SGB) is more effective than a PNB alone in reducing these responses in women undergoing modified radical mastectomy (MRM). Methods: This is a prospective randomized controlled trial. Fifty patients with breast cancer were randomly allocated to receive an ultrasound-guided PNB ( Results: The combined blockade group exhibited significantly lower IL-6 and TNF- Conclusion: In patients undergoing MRM, PNB combined with SGB block effectively blunted perioperative inflammatory response than PNB alone. A combined block approach can also alleviate stress response and postoperative acute pain with stable perioperative haemodynamics and better postoperative sleep quality.

Identifiers

PMID35707316
PMCPMC9192316
OpenAlexW4285740420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.