Evidence map›Paper›PMID 35706792›Full record

ArticleTranslational cancer research2022

Rationale and design of a prospective, multicenter, cohort study on the evaluation of postoperative Venous ThromboEmbolism incidence in patients with ColoRectal Cancer (CRC-VTE trial).

Qi Wei, Yang Wang, Yong-Bo An, Zheng-Yang Yang, Yi-Shan Liu, Xiao Zhang, Zhi-Chun Gu, Hong-Wei Yao, CRC-VTE investigators

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04588805 (Incidence Rate of Perioperiative Venous Thromboembolism), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04588805 unknown statusnot on this map

Incidence Rate of Perioperiative Venous Thromboembolism(VTE) in Colorectal Cancer Patients : a Multicenter Prospective Observational Cohort Study

TypeobservationalSponsorBeijing Friendship HospitalRan2020 to 2021Enrolled1,217ConditionsIncidence Rate of Perioperiative Venous Thromboembolism(VTE) in Colorectal Cancer Patients
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qi Wei *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yang Wang *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yong-Bo AnDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zheng-Yang YangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yi-Shan LiuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xiao ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zhi-Chun GuDepartment of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hong-Wei YaoDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
CRC-VTE investigators
Capital Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common complication after abdominal surgery. The incidence of VTE after colorectal malignancy is higher than that after general surgery. Although more attention has been paid to the prevention of VTE, there is still a large gap between clinical practice and guideline recommendation. Methods: The Venous ThromboEmbolism incidence in patients with ColoRectal Cancer (CRC-VTE trial) will be a prospective, multicenter, cohort study to determine the current status of the incidence, diagnosis, treatment, and prevention of VTE after colorectal cancer surgery in China, as well as to further improve the level of prevention and treatment of VTE events in these fragile patients. In this study, 1,217 patients will be enrolled at 40 centers in China and evaluated on VTE events and adverse events related to VTE prevention at 5-9 and 21-28 days after surgery. The primary outcome is the incidence of VTE events during the follow-up, and secondary outcome is the incidence of adverse events associated with VTE prevention. Discussion: This study will comprehensively evaluate the incidence and prevention of VTE after colorectal cancer surgery in China, balance the relationship between VTE prevention and bleeding adverse events, and the formulate a guideline for the prevention of VTE after colorectal surgery that might suitable for national conditions. Trial Registration: Clinical trial registration number NCT04588805 (The CRC-VTE trial).

Indexed as

anticoagulationcohortColorectal cancerlow molecular weight heparinoperationvenous thromboembolism (VTE)

Identifiers

PMID35706792
PMCPMC9189204
OpenAlexW4283027493

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.