Evidence map›Paper›PMID 35706753›Full record

ReviewCureus2022

Gastroesophageal Reflux Disease and Asthma: A Narrative Review.

Xavier A Grandes, Ramya Talanki Manjunatha, Salma Habib, Sai Lahari Sangaraju, Daniela Yepez

Abstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Exploring trends and predictors of long-term asthma remission.The World Allergy Organization journal · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xavier A GrandesResearch, Universidad Catolica Santiago de Guayaquil, Guayaquil, ECU.
Ramya Talanki ManjunathaInternal Medicine, Kempegowda Institute of Medical Sciences, Bangalore, IND.
Salma HabibMedicine and Surgery, Institute of Applied Health Sciences, Chittagong, BGD.
Sai Lahari SangarajuResearch, People's Education Society (PES) Institute of Medical Sciences and Research, Kuppam, IND.
Daniela YepezResearch, Universidad Catolica Santiago de Guayaquil, Guayaquil, ECU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) is defined by retrograde reflux of gastric contents to the esophagus leading to various signs and symptoms that range from heartburn/regurgitation to the development of extraesophageal respiratory syndromes like asthma. Although a cause-effect relationship has been proposed, evidence suggests that these two entities share a complex mechanism that may be reciprocal to each other. The understanding of the underlying mechanisms is imperial due to the fact that asthmatic patients may benefit from reflux therapy with subsequent improvement in pulmonary function testing and quality of life. This study has revised available literature in order to provide evidence for a nexus between GERD and asthma based on clinical correlation, pathophysiology, and pharmacologic management.

Indexed as

asthmaclinical correlationgastroesophageal reflux disease (gerd)pathophysiologypharmacologic management

Identifiers

PMID35706753
PMCPMC9187188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.