ArticleEClinicalMedicine2022
Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial.
Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Aerobic Exercise Training Response in Preterm-Born Young Adults with Elevated Blood Pressure and Stage 1 Hypertension: A Randomized Clinical Trial.American journal of respiratory and critical care medicine · 2023Trial
- Higher skeletal muscle mass is associated with higher blood pressure and left ventricular mass.Journal of hypertension · 2026Article
- Comparing four training modalities on body composition, cardiorespiratory fitness and cardiovascular responses in sedentary young men: a randomized trial.BMC sports science, medicine & rehabilitation · 2026Article
- Clinical study: Cardiovascular outcomes after a 14-week exercise intervention in young adults born preterm.Pediatric research · 2026Article
- Longitudinal Insights Into Pediatric Hypertension, Cardiac Consequences, and Physical Activity.Current hypertension reports · 2026Review
- Prematurity, Neonatal Complications, and the Development of Childhood Hypertension.JAMA network open · 2025Article
- Association of Device-Measured Habitual Sedentary Activity and Standing Posture With Blood Pressure and Hypertension in Danish Adults: The Lolland-Falster Health Study.Journal of the American Heart Association · 2025Observational
- Lung Function in a Multiethnic U.S. Cohort of Adolescents and Adults Born Preterm in the New BPD Era.Pediatric pulmonology · 2025Article
- Cardiovascular Health in the Transition From Adolescence to Emerging Adulthood: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2025Review
- Exercise Training Modalities in Young and Middle-Aged Adults With Prehypertension or Hypertension: A Systematic Review and Network Meta-Analysis.Health science reports · 2025Review
- Acute effects of isometric plank exercise on 24-hour ambulatory blood pressure in young adults with prehypertension: a randomized cross-over trial.Clinical hypertension · 2025Article
- Mediating Effects of Serum Lipids and Physical Activity on Hypertension Management of Urban Elderly Residents in China.Metabolites · 2024Article
- Lean Mass Longitudinally Confounds Sedentary Time and Physical Activity With Blood Pressure Progression in 2513 Children.Journal of cachexia, sarcopenia and muscle · 2024Article
- Cardiovascular responses to heat and cold exposure are altered by preterm birth in guinea pigs.Physiological reports · 2024Article
- Mediating effect of fat mass, lean mass, blood pressure and insulin resistance on the associations of accelerometer-based sedentary time and physical activity with arterial stiffness, carotid IMT and carotid elasticity in 1574 adolescents.Journal of human hypertension · 2024Article
- Impact of prematurity on lifelong cardiovascular health: structural and functional considerations.NPJ cardiovascular health · 2024Review
- A machine learning-based score for precise echocardiographic assessment of cardiac remodelling in hypertensive young adults.European heart journal. Imaging methods and practice · 2023Article
- Associations of accelerometer-based sedentary time, light physical activity and moderate-to-vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status.Scandinavian journal of medicine & science in sports · 2023Article
- Exercise Training Improves Exercise Capacity in Preterm-Born Adults: Lessons for Clinical Trials?American journal of respiratory and critical care medicine · 2023Article
- Physical Activity and Hypertension.Reviews in cardiovascular medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
Abstract
Background: Exercise is advised for young adults with elevated blood pressure, but no trials have investigated efficacy at this age. We aimed to determine whether aerobic exercise, self-monitoring and motivational coaching lowers blood pressure in this group. Methods: The study was a single-centre, open, two-arm, parallel superiority randomized clinical trial with open community-based recruitment of physically-inactive 18-35 year old adults with awake 24 h blood pressure 115/75mmHg-159/99 mmHg and BMI<35 kg/m Findings: Enrolment occurred between 30/06/2016-26/10/2018. Amongst the 203 randomized young adults ( Intepretation: These results do not support the exclusive use of moderate to high intensity aerobic exercise training for blood pressure control in young adults. Funding: Wellcome Trust, British Heart Foundation, National Institute for Health Research, Oxford Biomedical Research Centre.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.