Evidence map›Paper›PMID 35706441›Full record

ArticleCureus2022

Long-Lasting Efficacy of Radio Electric Asymmetric Conveyer Neuromodulation Treatment on Functional Dysmetria, an Adaptive Motor Behavior.

Vania Fontani, Arianna Rinaldi, Chiara Rinaldi, Laura Araldi, Alida Azzarà, Antonio M Carta, Nicoletta Casale, Alessandro Castagna, Maurizio Del Medico, Maurizio Di Stasio and 34 more

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Vania FontaniResearch, Rinaldi Fontani Foundation, Florence, ITA.
Arianna RinaldiBiomedical Sciences, University of Sassari, Sassari, ITA.
Chiara RinaldiNeuroscience, Psychology, Drug Area and Child Health (NEUROFARBA), University of Florence, Florence, ITA.
Laura AraldiInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Alida AzzaràObstetrics and Gynecology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Antonio M CartaInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Nicoletta CasaleInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Alessandro CastagnaRegenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.
Maurizio Del MedicoMedical Physics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Maurizio Di StasioInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Marina FacchiniNeurology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Monica GrecoGeriatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Savino LaMarcaOral Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Giovanni LoroDiabetes and Endocrinology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Anna MarroneInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Alessandra PalattellaPsychiatry, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Giulio PellegataAnesthesiology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Daniele RuiniFamily Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Corrado SchmittInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Franco VianiniInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Margherita MaioliBiomedical Sciences, University of Sassari, Sassari, ITA.
Carlo VenturaCardiology and Microbiology, National Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems, Bologna, ITA.
Franco CaltabianoSurgery and Urology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.
Adriano J BuenoOrthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Amélia Fugino MatuokaInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Edison Massahiro NabechimaInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Fabio A BechelliInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Fabricio da Silveira BossiSurgery, Endoscopy and Gastroenterology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Greice C Nitschke FontanaInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Jaques FinkielsztejnInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
José Alfredo Coelho PereiraResearch, Rinaldi Fontani Foundation, Florence, ITA.
Juarez Nunes CallegaroPsychiatry, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Kleiner Vasconcelos PinheiroIntegrative/Complementary Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Lara R Ferreira AlvesInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Marcelo Kodja DaguerOrthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Márcia C Marins MartinsPediatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Mauricio Bezerra UlianaOrthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Nelson Knop ZismanInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Paulo Cezar SchützOrthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Paulo R FochesatoInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Pollyanna Celso Felipe de CastroNeurology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Rosa M Tanaka NabechimaInternal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Roseli B RandonPediatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.
Salvatore RinaldiResearch, Rinaldi Fontani Foundation, Florence, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Fluctuating asymmetry (FA) is widely defined as the deviation from perfect bilateral symmetry and is considered an epigenetic measure of environmental stress. Rinaldi and Fontani hypothesized that the FA morpho-functional changes originate from an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by environmental stress. They called this phenomenon functional dysmetria (FD). On this premise, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction. Aims Previous studies showed that specific REAC neuro postural optimization (NPO) treatment can induce stable FD recovery. This study aimed to verify the duration of the NPO effect in inducing the stable FD recovery over time. Materials and methods Data were retrospectively collected from a population of 29,794 subjects who underwent a specific semiological FD assessment and received the NPO treatment, regardless of the pathology referred. Results The analysis of the data collected by the various participants in the study led us to ascertain the disappearance of FD in 100% of the cases treated, with a stability of the result detected up to 18 years after the single administration of the REAC NPO treatment. Conclusions The REAC NPO neurobiological modulation treatment consisting of a single administration surprisingly maintains a very long efficacy in the correction of FD. This effect can be explained as the long-lasting capacity of the NPO treatment to induce greater functional efficiency of the brain dynamics as proven in previous studies.

Indexed as

endogenous bioelectric activityepigeneticfunctional dysmetrianeurobiological modulationneuromodulationneuroplasticityneurostimulationneurotransmissionradio electric asymmetric conveyor

Identifiers

PMID35706441
PMCPMC9187162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.