Evidence map›Paper›PMID 35705672›Full record

ArticleScientific reports2022

Assessment of cortical inhibition depends on inter individual differences in the excitatory neural populations activated by transcranial magnetic stimulation.

Andris Cerins, Daniel Corp, George Opie, Michael Do, Bridgette Speranza, Jason He, Pamela Barhoun, Ian Fuelscher, Peter Enticott, Christian Hyde

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A New Angle on Transcranial Magnetic Stimulation Coil Orientation: A Targeted Narrative Review.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Review
  6. Modulation by Neuropeptides with Overlapping Targets Results in Functional Overlap in Oscillatory Circuit Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andris CerinsCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia. acerins@deakin.edu.au.
Daniel CorpCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
George OpieDiscipline of Physiology, School of Biomedicine, The University of Adelaide, Adelaide, SA, 5005, Australia.
Michael DoCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
Bridgette SperanzaCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
Jason HeDepartment of Forensic and Neurodevelopmental Sciences, Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
Pamela BarhounCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
Ian FuelscherCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
Peter EnticottCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.
Christian HydeCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood Campus, 221 Burwood Hwy, Burwood, VIC, 3125, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial magnetic stimulation (TMS) is used to probe inhibitory intracortical neurotransmission and has been used to infer the neurobiological dysfunction that may underly several neurological disorders. One technique, short-interval intracortical inhibition (SICI), indexes gamma-aminobutyric acid (GABA) mediated inhibitory activity and is a promising biomarker. However emerging evidence suggests SICI does not exclusively represent GABAergic activity because it may be influenced by inter-individual differences in the specific excitatory neural populations activated by TMS. Here we used the latency of TMS motor evoked potentials (MEPs) to index these inter-individual differences, and found that a significant proportion of the observed variability in SICI magnitude was accounted for by MEP latency, r = - 0.57, r

Indexed as

Motor CortexTranscranial Magnetic StimulationElectromyographyEvoked Potentials, MotorIndividualityNeural Inhibition

Identifiers

PMID35705672
PMCPMC9200840

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.