Evidence map›Paper›PMID 35705668›Full record

ArticleScientific reports2022

The histone H2B Arg95 residue links the pheromone response pathway to rapamycin-induced G

Abdallah Alhaj Sulaiman, Reem Ali, Mustapha Aouida, Balasubramanian Moovarkumudalvan, Dindial Ramotar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abdallah Alhaj SulaimanDivision of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box: 34110, Doha, Qatar.ORCID 0000-0002-6720-9269
Reem AliDivision of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box: 34110, Doha, Qatar.ORCID 0000-0003-2210-4241
Mustapha AouidaDivision of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box: 34110, Doha, Qatar.ORCID 0000-0001-7945-5320
Balasubramanian MoovarkumudalvanDivision of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box: 34110, Doha, Qatar.ORCID 0000-0003-1140-883X
Dindial RamotarDivision of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box: 34110, Doha, Qatar. dramotar@hbku.edu.qa.ORCID 0000-0002-9572-7223
Hamad bin Khalifa University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapamycin is an immunosuppressant used for treating many types of diseases such as kidney carcinomas. In yeast, rapamycin inhibits the TORC1 kinase signaling pathway causing rapid alteration in gene expression and ultimately cell cycle arrest in G

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdaptor Proteins, Signal TransducingCyclinsFungal ProteinsHistonesMechanistic Target of Rapamycin Complex 1Mitogen-Activated Protein KinasesPheromonesSirolimusAdaptor Proteins, Signal TransducingCLN2 protein, S cerevisiaeCyclinsFungal ProteinsFUS3 protein, S cerevisiaeHistonesKSS1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 1Mitogen-Activated Protein KinasesPheromonesSaccharomyces cerevisiae ProteinsSirolimusSTE5 protein, S cerevisiae

Identifiers

PMID35705668
PMCPMC9200821
OpenAlexW4282913573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.