Evidence map›Paper›PMID 35705306›Full record

ArticleRMD open2022

Active counselling and well-controlled disease result in a higher percentage of women with rheumatoid arthritis that breast feed: results from the PreCARA study.

Erik Kemper, Nafise Ghalandari, Hetty Wintjes, Anneke Van Steensel-Boon, Laura Kranenburg, Annemarie Mulders, Hubertina Crijns, Hieronymus Smeele, Radboud J Em Dolhain

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Erik KemperErasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0003-3540-9896
Nafise GhalandariCollege ter Beoordeling van Geneesmiddelen, Utrecht, The Netherlands n.ghalandari@erasmusmc.nl.
Hetty WintjesRheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Anneke Van Steensel-BoonRheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Laura KranenburgRheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0001-5201-0938
Annemarie MuldersGynaecology and Obstetrics, Erasmus Medical Center, Rotterdam, The Netherlands.
Hubertina CrijnsCollege ter Beoordeling van Geneesmiddelen, Utrecht, The Netherlands.
Hieronymus SmeeleRheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0001-7724-7712
Radboud J Em DolhainRheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Erasmus MC · NLMedicines Evaluation Board · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPrevious research has demonstrated that patients with rheumatoid arthritis (RA) are less likely to breast feed their offspring. Treatment options for RA during lactation have expanded and the importance of counselling is recognised. The aim of the current research was to study breast feeding among women with RA who benefit from these developments.

methodsPatients were derived from the Preconceptional Counselling in Active Rheumatoid Arthritis (PreCARA) cohort. Patients were treated according to a modified treat-to-target approach aimed at remission and received pregnancy counselling, including counselling on breast feeding. Postpartum visits were scheduled at 4-6, 12 and 26 weeks post partum. Prevalence of breast feeding at each postpartum visit was compared with a historical reference cohort (Pregnancy-induced Amelioration of Rheumatoid Arthritis cohort) and the general population.

resultsData on 171 pregnancies were available for the current analysis. 120 (70.2%) patients with RA initiated breast feeding. 103/171 (60.2%), 68/171 (39.8%) and 45/171 (26.3%) patients with RA breast fed their offspring at 4-6, 12 and 26 weeks post partum, respectively. These percentages were higher at all postpartum visits compared with the historical reference cohort (p<0.001). In comparison with the general population, the rates were similar at each time point.

conclusionPatients with RA in the PreCARA cohort were more likely to breast feed their offspring compared with patients with RA in the historical reference cohort. The breastfeeding rates observed were similar to breastfeeding rates among women in the general population. The increase in breast feeding among patients with RA may be due to the extension of lactation-compatible medication and pregnancy counselling.

Indexed as

Arthritis, RheumatoidBreast FeedingCounselingFemaleHumansLactationPostpartum PeriodPregnancyArthritis, RheumatoidAutoimmune DiseasesTumor Necrosis Factor Inhibitors

Identifiers

PMID35705306
PMCPMC9204414
OpenAlexW4282944167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.