Evidence map›Paper›PMID 35705275›Full record

ReviewInternal medicine (Tokyo, Japan)2023

Concurrent de novo Thymoma-associated Paraneoplastic Type 1 Autoimmune Hepatitis and Pure Red Cell Aplasia after Thymectomy: A Case Report and Literature Review.

Rie Sakata, Po-Sung Chu, Miho Kawaida, Katsura Emoto, Masatoshi Sakurai, Risa Nishida, Keisuke Asakura, Rei Morikawa, Nobuhito Taniki, Keisuke Kataoka and 2 more

Open access · diamondAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rie SakataDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Po-Sung ChuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Miho KawaidaDivision of Diagnostic Pathology, Keio University School of Medicine, Japan.
Katsura EmotoDivision of Diagnostic Pathology, Keio University School of Medicine, Japan.
Masatoshi SakuraiDivision of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Risa NishidaDivision of Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Japan.
Keisuke AsakuraDivision of Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Japan.
Rei MorikawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Nobuhito TanikiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Keisuke KataokaDivision of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Takanori KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Nobuhiro NakamotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Keio University · JPKeio University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precise manipulation of immune tolerance is the holy grail of immunotherapies for both autoimmunity and cancer immunity. Thymomas are well known to be associated with autoimmune diseases. The exact mechanism by which autoreactivity is induced after thymectomy remains to be elucidated. We herein present the case of a 50-year-old lady with concurrent de novo type 1 autoimmune hepatitis (AIH) and pure red cell aplasia (PRCA), 1 month after undergoing a successful total thymectomy for combined squamous cell carcinoma and thymoma (Masaoka stage II). Corticosteroids yielded short-term effects for both AIH and PRCA. Literature on thymoma-associated AIH, an extremely rare immune-related comorbidity, was also reviewed.

Indexed as

Hepatitis, AutoimmuneRed-Cell Aplasia, PureThymomaThymus NeoplasmsAutoantibodiesFemaleHumansMiddle AgedThymectomyAutoantibodiesautoimmunityimmune toleranceimmunosuppressionthymic epithelial tumors

Identifiers

PMID35705275
PMCPMC9908397
OpenAlexW4283031485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.