Evidence map›Paper›PMID 35705274›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Biclonal Diffuse Large B-cell Lymphoma Commonly Characterized by Partial Trisomy 18q Involving MALT1 and BCL2.

Katsuya Yamamoto, Shinichiro Kawamoto, Ruri Chijiki, Marika Watanabe, Sakuya Matsumoto, Akihito Kitao, Yu Mizutani, Kazuyoshi Kajimoto, Yoshitake Hayashi, Kimikazu Yakushijin and 1 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Katsuya YamamotoDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Shinichiro KawamotoDepartment of Transfusion Medicine and Cell Therapy, Kobe University Hospital, Japan.
Ruri ChijikiDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Marika WatanabeDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Sakuya MatsumotoDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Akihito KitaoDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Yu MizutaniDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Kazuyoshi KajimotoDivision of Molecular Medicine and Medical Genetics, Department of Pathology, Kobe University Graduate School of Medicine, Japan.
Yoshitake HayashiDivision of Molecular Medicine and Medical Genetics, Department of Pathology, Kobe University Graduate School of Medicine, Japan.
Kimikazu YakushijinDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Hironobu MinamiDivision of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan.
Kobe University · JPKobe University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 68-year-old man was admitted because of a left shoulder mass and swollen right testis. Pathological examinations indicated a diagnosis of diffuse large B-cell lymphoma (DLBCL) with the CD20+BCL6+MUM1+BCL2+CD10-MYC- phenotype in both lesions. G-banding of soft tissue showed 47,XY,+18, whereas testicular cells showed 47,X,+X,-Y,der (4) t (4;18) (p15;?),del (5) (q?),+13. Fluorescence in situ hybridization detected additional MALT1 and BCL2 signals in both lesions. Southern blot demonstrated different IGH rearrangements between the soft tissue and testis. The patient was diagnosed with biclonal DLBCL with different karyotypes but similar immunophenotypes. Partial trisomy 18q involving MALT1 and BCL2 may be commonly involved in the pathogenesis of this biclonal DLBCL.

Indexed as

Lymphoma, Large B-Cell, DiffuseTrisomyChromosomes, Human, Pair 18HumansIn Situ Hybridization, FluorescenceMaleMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinProto-Oncogene Proteins c-bcl-2Translocation, GeneticBCL2 protein, humanMALT1 protein, humanMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinProto-Oncogene Proteins c-bcl-2BCL2biclonal B-cell lymphomadiffuse large B-cell lymphomaMALT1trisomy 18

Identifiers

PMID35705274
PMCPMC9908399
OpenAlexW4283031824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.