Evidence map›Paper›PMID 35704994›Full record

ArticleImmunity2022

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Roshni Roy, Senthilkumar Ramamoorthy, Benjamin D Shapiro, Mary Kaileh, Dena Hernandez, Dimitra Sarantopoulou, Sampath Arepalli, Sö Ren Boller, Amit Singh, Arsun Bektas and 20 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors.

Roshni Roy
Senthilkumar Ramamoorthy
Benjamin D Shapiro
Mary Kaileh
Dena Hernandez
Dimitra Sarantopoulou
Sampath Arepalli
Sö Ren Boller
Amit Singh
Arsun Bektas
Jaekwan Kim
Ann Zenobia Moore
Toshiko Tanaka
Julia McKelvey
Linda Zukley
Cuong Nguyen
Tonya Wallace
Christopher Dunn
Robert Wersto
William Wood
Yulan Piao
Kevin G Becker
Christopher Coletta
Supriyo De
Jyoti Misra Sen
Alexis Battle
Nan-Ping Weng
Rudolf Grosschedl
Luigi Ferrucci
Ranjan Sen

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
GESTALT-Genetic and Epigenetic Signatures of Translational Aging Laboratory TestingZIAAG000996 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2015 to 2025
$7.6M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.