Evidence map›Paper›PMID 35704839›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2022

Prenatal DNA Sequencing for Fetal Aneuploidy Also Detects Maternal Cancer: Importance of Timely Workup and Management in Pregnant Women.

Amy E Turriff, Christina M Annunziata, Diana W Bianchi

Registry-linked trialOpen access · bronzeAbstract readEditorialComment
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04049604 (Incidental Detection of Maternal Neoplasia Through Non-invasive Cell-Free DNA Analysis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04049604 narecruitingnot on this map

Incidental Detection of Maternal Neoplasia Through Non-invasive Cell-Free DNA Analysis (IDENTIFY), a Natural History Study

TypeinterventionalSponsorNational Human Genome Research Institute (NHGRI)Ran2019 to 2029Enrolled365ConditionsMaternal NeoplasiaArmsNIPT
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Cancer in pregnancy: FIGO Best practice advice and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amy E TurriffPrenatal Genomics & Therapy Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0002-8065-7445
Christina M AnnunziataWomen's Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD.ORCID 0000-0003-2033-6532
Diana W BianchiPrenatal Genomics & Therapy Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0001-9270-5267
National Institutes of Health · USNational Cancer Institute · US

Funding

Clinical trials in womens cancersZIABC011584 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ANNUNZIATA, CHRISTINA · 2014 to 2023
$3.1M
Sequence Analysis of Circulating Cell-free DNA During PregnancyZIAHG200400 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BIANCHI, DIANA · 2018 to 2025
$524k
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NeoplasmsPregnant PeopleAneuploidyFemaleHumansPregnancySequence Analysis, DNA

Identifiers

PMID35704839
PMCPMC9467676
OpenAlexW4282968638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.