Evidence map›Paper›PMID 35704590›Full record

ArticleScience advances2022

A long noncoding RNA promotes parasite differentiation in African trypanosomes.

Fabien Guegan, K Shanmugha Rajan, Fábio Bento, Daniel Pinto-Neves, Mariana Sequeira, Natalia Gumińska, Seweryn Mroczek, Andrzej Dziembowski, Smadar Cohen-Chalamish, Tirza Doniger and 5 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  12. Non-coding RNAs as emerging players inFrontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Fabien GueganInstituto de Medicina Molecular-Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0001-9393-2920
K Shanmugha RajanThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.ORCID 0000-0003-4826-9802
Fábio BentoInstituto de Medicina Molecular-Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0002-0786-3912
Daniel Pinto-NevesInstituto de Medicina Molecular-Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Mariana SequeiraInstituto de Medicina Molecular-Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0003-1486-5403
Natalia GumińskaLaboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.ORCID 0000-0002-4599-2897
Seweryn MroczekLaboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.ORCID 0000-0001-5026-1741
Andrzej DziembowskiLaboratory of RNA Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.ORCID 0000-0001-8492-7572
Smadar Cohen-ChalamishThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.
Tirza DonigerThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.ORCID 0000-0001-6708-8404
Beathrice GaliliThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.
Antonio M EstévezInstituto de Parasitologia y Biomedicina 'Lopez-Neyra,' IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento 17, 18016 Armilla, Granada, Spain.ORCID 0000-0002-8272-5405
Cedric NotredameCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain.ORCID 0000-0003-1461-0988
Shulamit MichaeliThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.ORCID 0000-0002-9895-0439
Luisa M FigueiredoInstituto de Medicina Molecular-Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0002-5752-6586
Bar-Ilan University · ILUniversity of Lisbon · PTInternational Institute of Molecular and Cell Biology · PLInstituto de Parasitología y Biomedicina "López - Neyra" · ESUniversitat Pompeu Fabra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parasite

Identifiers

PMID35704590
PMCPMC9200285
OpenAlexW4282975612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.