Evidence map›Paper›PMID 35704518›Full record

ReviewAngewandte Chemie (International ed. in English)2022

Miniaturized Chemical Tags for Optical Imaging.

Sam Benson, Fabio de Moliner, William Tipping, Marc Vendrell

Open access · hybridAbstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sam BensonCentre for Inflammation Research, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.
Fabio de MolinerCentre for Inflammation Research, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.
William TippingCentre for Molecular Nanometrology, The University of Strathclyde, Glasgow, G1 1RD, UK.
Marc VendrellCentre for Inflammation Research, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.ORCID 0000-0002-5392-9740
Centre for Inflammation Research · GBUniversity of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in optical bioimaging have prompted the need for minimal chemical reporters that can retain the molecular recognition properties and activity profiles of biomolecules. As a result, several methodologies to reduce the size of fluorescent and Raman labels to a few atoms (e.g., single aryl fluorophores, Raman-active triple bonds and isotopes) and embed them into building blocks (e.g., amino acids, nucleobases, sugars) to construct native-like supramolecular structures have been described. The integration of small optical reporters into biomolecules has also led to smart molecular entities that were previously inaccessible in an expedite manner. In this article, we review recent chemical approaches to synthesize miniaturized optical tags as well as some of their multiple applications in biological imaging.

Indexed as

Fluorescent DyesOptical ImagingAmino AcidsAmino AcidsFluorescent DyesBioconjugatesFluorophoresProbesRaman Spectroscopy

Identifiers

PMID35704518
PMCPMC9542129
OpenAlexW4282941243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.