ArticlePlant physiology2022
CLASS-II KNOX genes coordinate spatial and temporal ripening in tomato.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 20 citations in OpenAlex.
- A Novel Homeobox Family Gene, ScH1-33, Promotes Tillering and Enhances Cold Tolerance in Sugarcane.Plant, cell & environment · 2026Article
- KNOX II Transcription Factor HOS59 Regulates Gypsy Transposable Elements to Modulate Panicle Development in Rice.Plant, cell & environment · 2026Article
- Regulation of the growth-to-ripening transition in tomato fruits by energy charge involving SlATP-PRT and SlAPRT1.Molecular horticulture · 2026Article
- Genome-Wide Analysis of thePlants (Basel, Switzerland) · 2026Article
- The KNOX transcription factor ClSP activates ClAPRR2 to regulate dark green stripe formation in watermelon.Plant biotechnology journal · 2025Article
- Genome-Wide Analysis ofPlants (Basel, Switzerland) · 2025Article
- Article
- AGAMOUS-LIKE24 controls pistil number in Japanese apricot by targeting the KNOTTED1-LIKE gene KNAT2/6-a.Plant physiology · 2024Article
- Rewiring of a KNOXI regulatory network mediated by UFO underlies the compound leaf development in Medicago truncatula.Nature communications · 2024Article
- New Advances in the Study of Regulation of Tomato Flowering-Related Genes Using Biotechnological Approaches.Plants (Basel, Switzerland) · 2024Review
- Genome-Wide Identification of theGenes · 2023Article
- Article
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Authors and funding
14 authors at 4 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Fruits can be divided into dry and fleshy types. Dry fruits mature through senescence and fleshy fruits through ripening. Previous studies have indicated that partially common molecular networks could govern fruit maturation in these different fruit types. However, the nature of such networks remains obscure. CLASS-II KNOX genes were shown to regulate the senescence of the Arabidopsis (Arabidopsis thaliana) dry fruits, the siliques, but their roles in fleshy-fruit development are unknown. Here, we investigated the roles of the tomato (Solanum lycopersicum) CLASS-II KNOX (TKN-II) genes in fleshy fruit ripening using knockout alleles of individual genes and an artificial microRNA line (35S:amiR-TKN-II) simultaneously targeting all genes. 35S:amiR-TKN-II plants, as well as a subset of tkn-II single and double mutants, have smaller fruits. Strikingly, the 35S:amiR-TKN-II and tknII3 tknII7/+ fruits showed early ripening of the locular domain while their pericarp ripening was stalled. Further examination of the ripening marker-gene RIPENING INHIBITOR (RIN) expression and 35S:amiR-TKN-II rin-1 mutant fruits suggested that TKN-II genes arrest RIN activity at the locular domain and promote it in the pericarp. These findings imply that CLASS-II KNOX genes redundantly coordinate maturation in both dry and fleshy fruits. In tomato, these genes also control spatial patterns of fruit ripening, utilizing differential regulation of RIN activity at different fruit domains.
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