Evidence map›Paper›PMID 35703724›Full record

SynthesisRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2022

COVID-19 cutaneous manifestations in children and adolescents: a systematic review.

Ricardo Pasquini Neto, Felipe Antonio Torres Mazzo, Fernanda de Almeida Vieira, Gustavo de Souza Bueno, João Vitor Correa Previdi, Lara Rozetti da Silva, Nasthia Kreuz Baziulis da Silva, Joseph Lucius Jorizzo, Felipe Bochnia Cerci

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ricardo Pasquini NetoPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-3063-5061
Felipe Antonio Torres MazzoPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-5378-1558
Fernanda de Almeida VieiraPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-6323-3213
Gustavo de Souza BuenoPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-2965-9517
João Vitor Correa PrevidiPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-7352-1737
Lara Rozetti da SilvaPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-7762-5450
Nasthia Kreuz Baziulis da SilvaPontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-0233-4955
Joseph Lucius JorizzoWake Forest University, Winston-Salem, NC, United States of America.ORCID http://orcid.org/0000-0002-2590-970X
Felipe Bochnia CerciUniversidade Federal do Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-9605-0798
Pontifícia Universidade Católica do Paraná · BRCornell University · USUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the coronavirus disease 2019 (COVID-19) cutaneous manifestations described in pediatric patients and discuss their relevance for early diagnosis. DATA SOURCE: The study consisted of a systematic review of original articles indexed in PubMed and Embase databases, as well as gray literature articles found through Google Scholar. A search strategy, based on PICO (Patient, Intervention, Comparison, Outcome) Tool, with the terms "child," "infant," "childhood," "adolescents," "teenagers," "COVID-19," "SARS-CoV-2," and "skin manifestations," was performed to optimize the findings. The study did not restrict any article regarding language. DATA SYNTHESIS: Out of the 310 articles that initially met the inclusion criteria, 35 were selected for review, totalizing 369 patients. The most common COVID-19 cutaneous manifestations in children and adolescents were Chilblain-like lesions, presented in 67.5% of the cases, followed by erythema multiforme-like (31.7%) and varicella-like lesions (0.8%). The Chilblain-like lesions appeared 7.6 days (95%CI 7.4-7.8) after the viral infection and lasted for 17.5 days (95%CI 16.5-18.5), erythema multiforme-like lesions appeared in 9.5 days (95%CI 9-10) and lasted for 10.3 days (95%CI 9.1-11.5), and varicella-like lesions appeared in 12.3 days (95%CI 4-20.6) and lasted for 7 days.

conclusionsKnowledge of the different skin manifestations in children and adolescents with COVID-19 is essential for an early diagnosis and, consequently, the possibility of promptly care adoption as well as to interrupt the new coronavirus transmission chains in the current pandemic context.

Indexed as

ChickenpoxChilblainsCOVID-19Erythema MultiformeSkin DiseasesAdolescentChildHumansInfantSARS-CoV-2

Identifiers

PMID35703724
PMCPMC9190479
OpenAlexW4285106062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.