Evidence map›Paper›PMID 35703559›Full record

ArticlemSystems2022

MAGNETO: An Automated Workflow for Genome-Resolved Metagenomics.

Benjamin Churcheward, Maxime Millet, Audrey Bihouée, Guillaume Fertin, Samuel Chaffron

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Benjamin ChurchewardNantes Université, École Centrale Nantes, CNRS, LS2N, UMR 6004, Nantes, France.
Maxime MilletNantes Université, École Centrale Nantes, CNRS, LS2N, UMR 6004, Nantes, France.
Audrey BihouéeNantes Université, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Guillaume FertinNantes Université, École Centrale Nantes, CNRS, LS2N, UMR 6004, Nantes, France.
Samuel ChaffronNantes Université, École Centrale Nantes, CNRS, LS2N, UMR 6004, Nantes, France.
Nantes Université · FRCentre National de la Recherche Scientifique · FRÉcole Centrale de Nantes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metagenome-assembled genomes (MAGs) represent individual genomes recovered from metagenomic data. MAGs are extremely useful to analyze uncultured microbial genomic diversity, as well as to characterize associated functional and metabolic potential in natural environments. Recent computational developments have considerably improved MAG reconstruction but also emphasized several limitations, such as the nonbinning of sequence regions with repetitions or distinct nucleotidic composition. Different assembly and binning strategies are often used; however, it still remains unclear which assembly strategy, in combination with which binning approach, offers the best performance for MAG recovery. Several workflows have been proposed in order to reconstruct MAGs, but users are usually limited to single-metagenome assembly or need to manually define sets of metagenomes to coassemble prior to genome binning. Here, we present MAGNETO, an automated workflow dedicated to MAG reconstruction, which includes a fully-automated coassembly step informed by optimal clustering of metagenomic distances, and implements complementary genome binning strategies, for improving MAG recovery. MAGNETO is implemented as a Snakemake workflow and is available at: https://gitlab.univ-nantes.fr/bird_pipeline_registry/magneto.

Indexed as

MetagenomicsMicrobiotaGenome, MicrobialMetagenomeWorkflowcomputational workflowmetagenome-assembled genomesmetagenomicsmicrobiomes

Identifiers

PMID35703559
PMCPMC9426564
OpenAlexW4282983820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.