SynthesisInvestigative ophthalmology & visual science2022
Choroidal Thickness and Its Association With Age, Axial Length, and Refractive Error in Chinese Adults.
Synthesis in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Choroidal vascularity index is independent of ocular and image-based factors in healthy eyes: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Association of macular outward scleral height with axial length, macular choroidal thickness and morphologic characteristics of the optic disc in Chinese adults.Eye (London, England) · 2024Trial
- Clinical observation and correlation between the different degrees of myopia and choroidal thickness in children and adolescents.Medicine · 2026Article
- Fellow-eye retinal age gap and high injection burden over four years in neovascular age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Vortex Vein Morphology and Choroidal Thickness as Predictors of Refractive Status: Model Construction and Mediation Analysis.Translational vision science & technology · 2026Article
- Association between arterial stiffness and choroidal vascular in type 2 diabetes: more pronounced in individuals aged 30 to 50 years.International ophthalmology · 2026Article
- Associations Between Choroidal Structural Parameters and Cone Photoreceptors in Young High Myopia.Translational vision science & technology · 2026Article
- Choroidal Changes after Intravitreal Aflibercept, Faricimab, Brolucizumab, and High-Dose Aflibercept in Treatment-Naïve Neovascular Age-Related Macular Degeneration.Ophthalmology science · 2026Article
- Regional choroidal perfusion deficits and vector-based choroidal associations in adolescent astigmatism.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Pachychoroid-Related Pigment Epithelial Detachment Treated with Photodynamic Therapy.Biomedicines · 2026Article
- Imaging the choroidal microvasculature in intensive and high dependency care unit patients: a pilot study.BMJ open · 2026Article
- Effects of small incision lenticule extraction and femtosecond laser-assistedExperimental and therapeutic medicine · 2026Article
- Clinical spectrum and prevalence associations of chorioretinal damage in high myopia: a retrospective cross-sectional analysis.Frontiers in medicine · 2026Article
- Clinical characteristics and risk factors for corneal guttae in Japanese cataract patients.Japanese journal of ophthalmology · 2026Observational
- Choroidal thickness and peripapillary RNFL in relation to axial length and progression in myopic children.Frontiers in bioengineering and biotechnology · 2026Article
- Associations between axial length and optical coherence tomography angiography biomarkers.International journal of retina and vitreous · 2025Article
- Blue Light Defocus Induces A Positive Effect on Refractive Status and Ocular Health: A Randomized Crossover Trial.Global challenges (Hoboken, NJ) · 2025Article
- Multimodal imaging of sympathetic ophthalmia with florid peripapillary choroidal neovascularization - a case report.American journal of ophthalmology case reports · 2025Article
- Three-dimensional choroidal parameter differences in myopic anisometropia.BMC ophthalmology · 2025Article
- Quantitative Choroidal Analysis of Molecularly Characterized Retinitis Pigmentosa.Investigative ophthalmology & visual science · 2025Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To identify the association between the choroidal thickness (ChT) with age and axial length (AL) under different refractive errors (REs) in Chinese adults. Methods: Swept-source optical coherence tomography was used to measure ChT in 2126 right eyes of 2126 participants. The participants were classified as having pathologic myopia (PM), high myopia without PM (HM), low myopia (LM), and nonmyopia (non-M) according to their REs and META-PM (the Meta-Analysis of Pathologic Myopia) classification criteria. Results: The mean age was 52.49 ± 20.39 years (range, 18-93 years), and the mean RE was -5.27 ± 5.37 diopters (D; range, -25.5 to +7.75 D). The mean average ChT was 159.25 ± 80.75 µm and decreased in a linear relationship from non-M to PM (190.04 ± 72.64 µm to 60.99 ± 37.58 µm, P < 0.001). A significant decline in ChT was noted between 50 and 70 years (r = -0.302, P < 0.001) and less rapidly after the age of 70 years (r = -0.105, P = 0.024). No correlation was noted between age and ChT under 50 years (P = 0.260). A significantly higher association with AL was noted in the central fovea (βHM = -23.92, βLM = -23.88, βNon-M = -18.80, all P < 0.001) and parafoveal ChT (βHM = -22.87, βLM = -22.31, βNon-M = -18.61, all P < 0.001) when compared with the perifoveal region (βHM = -19.80, βLM = -18.29, βNon-M = -13.95, all P < 0.001). Within each group of PM, HM, LM, and non-M, regression analysis showed that the coefficients of age and AL with different macular regions of ChT varied significantly. Conclusions: ChT was negatively correlated with age after 50 years. The thinning of the choroid was more prominent in the center and parafoveal regions as AL increased. Varied distributions of ChT decrease associated with AL and age were noted among different refractive groups.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.