Evidence map›Paper›PMID 35703530›Full record

ArticleThe Eurasian journal of medicine2022

Comparison of Serum Adropin Levels in Patients with Diabetes Mellitus, COVID-19, and COVID-19 with Diabetes Mellitus.

Pelin Aydın, Sevgi Karabulut Uzunçakmak, İbrahim Hakkı Tör, Arzu Bilen, Ayşe Özden

Open access · diamondAbstract read
In one paragraph

Article in The Eurasian journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. SARS-CoV-2 Infection and Candidate Biomarkers.The Eurasian journal of medicine · 2022
    Article
  7. Article
  8. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Pelin AydınDepartment of Anesthesiology and Reanimation, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Sevgi Karabulut UzunçakmakDepartment of Health Services, Bayburt University Vocational School, Bayburt, Turkey.
İbrahim Hakkı TörDepartment of Anesthesiology and Reanimation, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Arzu BilenDepartment of Internal Medicine, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Ayşe ÖzdenDepartment of Pediatric Endocrinology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Erzurum Regional Training and Research Hospital · TRAtatürk University · TRBayburt University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn the present study, the relationship between a poor prognosis and adropin levels in diabetic patients with coronavirus disease 2019 was investigated by measuring serum adropin levels and levels of D-dimer, C-reactive protein, and ferritin, which are considered prognostic factors for coronavirus disease 2019. MATERIALS AND

methodsHundred volunteer participants treated in the Erzurum Regional Training and Research Hospital were included in this study. Serum adropin levels were measured by enzyme-linked immunosorbent assay. The relationship between serum adropin level and C-reactive protein, ferritin, and D-dimer levels was analyzed by correlation analysis.

resultsThe participants' serum adropin levels differed between the groups (P = .0007). The control group had the highest adropin levels among groups. The lowest adropin levels were in the COVID + diabetes mel- litus group. Adropin levels of diabetes mellitus, COVID, and diabetes mellitus+COVID groups were sig- nificantly decreased when compared to the control (P < .05). There was a significant negative correlation between adropin and C-reactive protein, D-dimer, and ferritin.

conclusionAdropin can be used as an auxiliary biomarker, a prognostic factor in the early management of coronavirus disease 2019 patients with diabetes mellitus. We think that our study will guide future studies conducted in this field.

Identifiers

PMID35703530
PMCPMC9634878
OpenAlexW4281641222

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.