Evidence map›Paper›PMID 35703393›Full record

ArticleJournal of agricultural and food chemistry2022

High-Throughput Method for Wide-Coverage and Quantitative Phenolic Fingerprinting in Plant-Origin Foods and Urine Samples.

Raúl González-Domínguez, Ana Sayago, María Santos-Martín, Ángeles Fernández-Recamales

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raúl González-DomínguezAgrifood Laboratory, Faculty of Experimental Sciences, University of Huelva, 21007 Huelva, Spain.ORCID 0000-0002-7640-8833
Ana SayagoAgrifood Laboratory, Faculty of Experimental Sciences, University of Huelva, 21007 Huelva, Spain.
María Santos-MartínAgrifood Laboratory, Faculty of Experimental Sciences, University of Huelva, 21007 Huelva, Spain.
Ángeles Fernández-RecamalesAgrifood Laboratory, Faculty of Experimental Sciences, University of Huelva, 21007 Huelva, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of mass spectrometry is currently widespread in polyphenol research because of its sensitivity and selectivity, but its usual high cost, reduced robustness, and nonavailability in many analytical laboratories considerably hinder its routine implementation. Herein, we describe the optimization and validation of a high-throughput, wide-coverage, and robust metabolomics method based on reversed-phase ultra-high-performance liquid chromatography with diode array detection for the identification and quantification of 69 phenolic compounds and related metabolites covering a broad chemical space of the characteristic secondary metabolome of plant foods. The method was satisfactorily validated following the Food and Drug Administration guidelines in terms of linearity (4-5 orders of magnitude), limits of quantification (0.007-3.6 mg L

Indexed as

PhenolsPolyphenolsChromatography, High Pressure LiquidMass SpectrometryOlive OilOlive OilPhenolsPolyphenolsfood analysisliquid chromatography−diode array detectormetabolomicsphenolic compoundsurine

Identifiers

PMID35703393
PMCPMC10550202

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.