Evidence map›Paper›PMID 35703353›Full record

ArticleEpigenetics2022

Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region.

Wenwen Wang, Suxu Tan, Yujia Yang, Tao Zhou, De Xing, Baofeng Su, Jinhai Wang, Shangjia Li, Mei Shang, Dongya Gao and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Wenwen WangSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Suxu TanSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Yujia YangSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Tao ZhouSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
De XingSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Baofeng SuSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Jinhai WangSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Shangjia LiSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Mei ShangSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Dongya GaoDepartment of Biology, College of Arts and Sciences, Syracuse University, Syracuse, NY, USA.
Rex DunhamSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.
Zhanjiang LiuDepartment of Biology, College of Arts and Sciences, Syracuse University, Syracuse, NY, USA.
Auburn University · USFlorida State University · USXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exogenous oestrogen 17β-oestradiol (E2) has been shown to effectively induce feminization in teleosts. However, the molecular mechanisms underlying the process remain unclear. Here, we determined global DNA methylation and gene expression profiles of channel catfish (

Indexed as

EstradiolFeminizationIctaluridaeAdrenergic AgentsAnimalsDNA MethylationEstrogensFemaleGonadotropin-Releasing HormoneMaleAdrenergic AgentsEstradiolEstrogensGonadotropin-Releasing Hormonemethylationoestrogensex differentiationSex reversalteleosttranscription

Identifiers

PMID35703353
PMCPMC9621036
OpenAlexW4282938934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.