ArticleKidney diseases (Basel, Switzerland)2022
Echocardiographic Findings and Genotypes in Autosomal Dominant Polycystic Kidney Disease.
Article in Kidney diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Polycystin-1 and Cardiac Remodeling: From Mechanotransduction to Clinical Consequences.Circulation research · 2026Review
- Sodium-Glucose Cotransporter 2 Inhibitors in Autosomal Dominant Polycystic Kidney Disease: Mechanistic Insights and Therapeutic Promise.Journal of the American Society of Nephrology : JASN · 2026Review
- Cardiac complications in autosomal dominant polycystic kidney disease: links to genotype and CKD severity.Clinical kidney journal · 2025Article
- Cardiovascular changes in Persian cats with polycystic kidney disease: a study of cardiac troponin I, echocardiography and blood pressure.Journal of feline medicine and surgery · 2025Article
- Echocardiographic characteristics of autosomal dominant polycystic kidney disease.Scientific reports · 2024Article
- Cardiovascular Manifestations and Management in ADPKD.Kidney international reports · 2023Review
- Echocardiographic Abnormalities in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patients.Journal of clinical medicine · 2022Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cystic kidney disease and is well known to have extrarenal complications. Cardiovascular complications are of particular clinical relevance because of their morbidity and mortality; however, unclear is why they occur so frequently in patients with ADPKD and whether they are related to the genotypes. Methods: We extracted and retrospectively analyzed clinical data on patients with ADPKD who underwent echocardiography and whose genotype was confirmed by genetic testing between April 2016 and December 2020. We used next-generation sequencing to compare cardiac function, structural data, and the presence of cardiac valvular disease in patients with 1 of 3 genotypes: Results: This retrospective study included 65 patients with ADPKD. Patients were divided into 3 groups: Conclusion: This study found a significantly higher prevalence of MR in patients with the
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