Evidence map›Paper›PMID 35702703›Full record

ArticleKidney diseases (Basel, Switzerland)2022

Extracellular Vesicles That Herald the Scarcity of Oxygen.

Sekyung Oh, Sang-Ho Kwon

Open access · goldAbstract read
In one paragraph

Article in Kidney diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Extracellular Vesicle MicroRNA in the Kidney.Comprehensive Physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Sekyung OhDepartment of Medical Science, Catholic Kwandong University College of Medicine, Incheon, Republic of Korea.
Sang-Ho KwonDepartment of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Augusta University · USCatholic Kwandong University · KR

Funding

Regulation of exosome release and its role in acute kidney injury.R01DK120510 · NIDDK · AUGUSTA UNIVERSITY · PI KWON, KENNETH · 2019 to 2023
$1.7M
NIDDK NIH HHS R01 DK120510
6 · The paper itself

Abstract

The natural, membrane-bound nanoscale particles, called extracellular vesicles (EVs) have emerged as an effective, versatile vehicle to transport desired drugs specifically to injury sites. Heralding the presence of the scarcity of oxygen, EVs produced from the cells upregulating the expression of the critical transcriptional regulator of hypoxia, HIF-1, can induce a response in ischemia-reperfusion-damaged cells to ameliorate renal tubular injury and inflammation.

Indexed as

ExosomesExtracellular vesiclesHypoxiaIschemiaKidney injury

Identifiers

PMID35702703
PMCPMC9149483
OpenAlexW4226317714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.