Evidence map›Paper›PMID 35702608›Full record

ArticleBioactive materials2023

A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis.

Mengna Li, Jing-Wei Xu, Jiayong Li, Wei Wang, Chenqi Luo, Haijie Han, Zhi-Kang Xu, Ke Yao

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Progress in the application of 3D printing technology in ophthalmology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  7. Progress in the application of 3D printing technology in ophthalmology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mengna LiEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Jing-Wei XuEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Jiayong LiEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Wei WangEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Chenqi LuoEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Haijie HanEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Zhi-Kang XuMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, PR China.
Ke YaoEye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative endophthalmitis (POE) has been the most threatening complication after cataract surgery, which perhaps can be solved by the antibiotic-loaded intraocular lens (IOL). However, most drug-loaded IOLs demonstrate insufficient drug quantity, short release time, increased implantation-related difficulties or other noticeable drawbacks. To prevent POE and to address these deficiencies, a drug-loaded copolymer IOL, prepared from poly (urethane acrylate) prepolymer, isobornyl methacrylate (IBOMA), N-vinyl-2-pyrrolidone (NVP), Irgacure 819, RUVA-93, and gatifloxacin (GAT), was rapidly fabricated via photocuring and by using a 3D-printed mold. This composite displayed an outstanding and controllable GAT release behavior

Indexed as

3D printingDrug delivery intraocular lensGatifloxacinPhotocuringPostoperative endophthalmitis

Identifiers

PMID35702608
PMCPMC9168518
OpenAlexW4281739773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.