ArticleIntractable & rare diseases research2022
Granulomatosis with polyangiitis in gingiva: A rare case of isolated presentation.
Article in Intractable & rare diseases research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Refractory Gingival Enlargement: A Critical Oral Clue to Early-Stage Granulomatosis With Polyangiitis-A Case Report and Literature Review.Case reports in dentistry · 2026Article
- Granulomatosis With Polyangiitis Presenting as Pulmonary Nodules: A Case Study and Literature Review.Case reports in immunology · 2026Article
- Strawberry Gingivitis as the Primary Sign of ANCA-Negative Granulomatosis With Polyangiitis (GPA): A Case Report.Clinical case reports · 2025Article
- When herpes masks a greater threat: A case report of granulomatosis with polyangiitis.Medicine · 2025Article
- Challenges in Differential Diagnosis of Diffuse Gingival Enlargement: Report of Two Representative Cases and Literature Review.Dentistry journal · 2024Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease characterized by necrotising granulomatous inflammation of upper and lower respiratory tract, vasculitis and glomerulonephritis. This ailment may present with cough, haemoptysis, sinusitis, nasal deformity, skin lesions, malaise, fever, anorexia, and weight loss. Oral manifestation includes strawberry gingivitis, which is a pathognomonic clinical presentation. Here, we present a case of GPA in gingiva as the first manifestation. Clinical examination of the oral cavity revealed granular, erythematous gingival enlargement in the lower anterior teeth region involving papilla, marginal and attached gingiva with shiny and pebbled surface. Histopathological examination showed pseudoepitheliomatous hyperplasia with vasculitis and inflammation in the connective tissue, neutrophilic infiltration and abscess formation with haemorrhage were noted. Laboratory investigations revealed Proteinase 3 (PR3) antigen and Glomerular basement membrane (GBM) antigen were positive. Clinical, histopathological and laboratory investigations enabled the diagnosis of Granulomatosis with Polyangiitis. We present this rare case report of GPA with primary manifestation in gingiva.
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