Evidence map›Paper›PMID 35702555›Full record

ArticleCase reports in oncology

Bone Marrow Carcinomatosis in a Stage IV Breast Cancer Patient Treated by Letrozole as First-Line Endocrine Therapy.

Tsuyoshi Nakagawa, Kumiko Hayashi, Ayumi Ogawa, Goshi Oda, Iichiro Onishi, Masahide Yamamoto, Mio Mori, Tomoyuki Fujioka, Toshiaki Ishikawa, Kentaro Okamoto and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tsuyoshi NakagawaDepartment of Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Kumiko HayashiDepartment of Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Ayumi OgawaDepartment of Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Goshi OdaDepartment of Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Iichiro OnishiDepartment of Pathology, Tokyo Medical and Dental University, Tokyo, Japan.
Masahide YamamotoDepartment of Hematology, Tokyo Medical and Dental University, Tokyo, Japan.
Mio MoriDepartment of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
Tomoyuki FujiokaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
Toshiaki IshikawaDepartment of Specialized Surgery, Graduated School, Tokyo Medical and Dental University, Tokyo, Japan.
Kentaro OkamotoDepartment of Specialized Surgery, Graduated School, Tokyo Medical and Dental University, Tokyo, Japan.
Hiroyuki UetakeDepartment of Specialized Surgery, Graduated School, Tokyo Medical and Dental University, Tokyo, Japan.
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow carcinomatosis (BMC) associated with breast cancer is a rare but often difficult-to-treat condition; we report a case of a female stage IV breast cancer patient in her seventies with BMC that improved with endocrine monotherapy. The patient had hemoglobinopenia and thrombocytopenia at the time of diagnosis. The diagnosis of BMC due to estrogen receptor-positive invasive lobular carcinoma was confirmed. After transfusion of 4 units of concentrated red blood cells, endocrine treatment with letrozole improved the hematopenia. Ten months after the treatment started, bone metastases worsened, so the patient was changed to combination therapy with palbociclib and fulvestrant, after which there was no worsening of the disease.

Indexed as

Bone marrow carcinomatosisBreast cancerEndocrine therapy

Identifiers

PMID35702555
PMCPMC9149407
OpenAlexW4224240227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.