Evidence map›Paper›PMID 35702495›Full record

ReviewBreast care (Basel, Switzerland)2022

Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer.

Kerstin Rhiem, Bernd Auber, Susanne Briest, Nicola Dikow, Nina Ditsch, Neda Dragicevic, Sabine Grill, Eric Hahnen, Judit Horvath, Bernadette Jaeger and 14 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Breast care (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. National policies for screening and early detection of breast cancer around the globe: Practices, barriers, and solutions.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Kerstin RhiemCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Cologne, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
Bernd AuberDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Susanne BriestDepartment of Obstetrics and Gynaecology, University Hospital of Leipzig, Leipzig, Germany.
Nicola DikowInstitute of Human Genetics, University of Heidelberg, Heidelberg, Germany.
Nina DitschDepartment of Gynecology and Obstetrics, University Hospital of Augsburg, Augsburg, Germany.
Neda DragicevicInstitute of Human Genetics, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Sabine GrillDepartment of Gynecology and Obstetrics, University Hospital Klinikum Rechts der Isar, Technical University Munich (TUM), Munich, Germany.
Eric HahnenCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Cologne, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
Judit HorvathInstitute for Human Genetics, University Hospital Münster, Münster, Germany.
Bernadette JaegerDepartment of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Karin KastCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Cologne, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
Marion KiechleDepartment of Gynecology and Obstetrics, University Hospital Klinikum Rechts der Isar, Technical University Munich (TUM), Munich, Germany.
Elena LeinertDepartment of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
Susanne MorlotDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Michael PüskenDepartment of Radiology, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
Dieter SchäferInstitute for Human Genetics, University of Frankfurt, Frankfurt, Germany.
Sarah SchottDepartment of Obstetrics and Gynaecology, University of Heidelberg, Heidelberg, Germany.
Christopher SchroederInstitute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany.
Ulrike Siebers-ReneltInstitute for Human Genetics, University Hospital Münster, Münster, Germany.
Christine SolbachDepartment of Gynecology and Obstetrics, University Hospital Frankfurt, Frankfurt, Germany.
Nana Weber-LassalleCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Cologne, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
Isabell WitzelDepartment of Obstetrics and Gynaecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christine Zeder-GößDepartment of Gynecology and Obstetrics, University Hospital of Augsburg, Augsburg, Germany.
Rita K SchmutzlerCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Cologne, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) has established a multigene panel (TruRisk®) for the analysis of risk genes for familial breast and ovarian cancer. Summary: An interdisciplinary team of experts from the GC-HBOC has evaluated the available data on risk modification in the presence of pathogenic mutations in these genes based on a structured literature search and through a formal consensus process. Key Messages: The goal of this work is to better assess individual disease risk and, on this basis, to derive clinical recommendations for patient counseling and care at the centers of the GC-HBOC from the initial consultation prior to genetic testing to the use of individual risk-adapted preventive/therapeutic measures.

Indexed as

BRCA1BRCA2ConsensusHereditary breast cancerHereditary ovarian cancerPanel testing

Identifiers

PMID35702495
PMCPMC9149395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.