ArticleRSC advances2022
The hydroperoxyl antiradical activity of natural hydroxycinnamic acid derivatives in physiological environments: the effects of pH values on rate constants.
Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The radical scavenging activity of monocaffeoylquinic acids: the role of neighboring hydroxyl groups and pH levels.RSC advances · 2024Article
- Modulation of the oxidative damage, inflammation, and apoptosis-related genes by dicinnamoyl-L-tartaric acid in liver cancer.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Density functional theory investigation of mechanisms of degradation reactions of sulfonated PEEK membranes with OH radicals in fuel cells: addition-elimination reactions and acid catalyzed water elimination.Theoretical chemistry accounts · 2023Article
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Authors and funding
3 authors.
Funding
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Abstract
Hydroxycinnamic acid derivatives (HCA) are a type of phenolic acid that occurs naturally. HCA are widely known for their anti-inflammatory, anti-cancer, and especially antioxidant capabilities; however, a comprehensive study of the mechanism and kinetics of the antiradical activity of these compounds has not been performed. Here, we report a study on the mechanisms and kinetics of hydroperoxyl radical scavenging activity of HCA by density functional theory (DFT) calculations. The ability of HCA to scavenge hydroperoxyl radicals in physiological environments was studied. The results showed that HCA had moderate and weak HOO˙ antiradical activity in pentyl ethanoate solvent, with the overall rate constant
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