ArticleFood science & nutrition2022
Inhibitory effects of saeu-jeot extract on NLRP3 inflammasome activation and radiation-induced micronucleus formation.
Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Inhibitory effects of saeu-jeot extract on NLRP3 inflammasome activation and radiation-induced micronucleus formation.Food science & nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Saeu-jeot, or shrimp paste, is a traditional Korean high-salt fermented seafood. This study elucidated the effects of saeu-jeot extract (SJE) on NLRP3 inflammasome activation and radiation-induced micronucleus formation. Method: We treated lipopolysaccharide-primed mouse bone marrow-derived macrophages with the NLRP3 inflammasome activators ATP and nigericin. We also analyzed the acute effects of ionizing radiation on micronucleated polychromatic erythrocytes (MnPCEs) in whole-body gamma-irradiated male BALB/c and C57BL/6 mice after oral administration of SJE. Results: SJE significantly inhibited NLRP3 inflammasome activation, reducing IL-1β secretion in vitro. In addition, the frequency of MnPCEs was significantly lower in SJE-treated mice. Conclusions: SJE has anti-inflammatory effects and reduces radiation-induced chromosome damage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.