ArticleAmerican journal of translational research2022
Serum IL-6 as a marker of disease progression in interstitial nephritis.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Identification of the key targets for sepsis-associated acute kidney injury by RNA sequencing combined with bioinformatics methods.BMC immunology · 2024Article
- Data driven analysis reveals prognostic genes and immunological targets in human sepsis-associated acute kidney injury.World journal of emergency medicine · 2024Article
- The components of tumor microenvironment as biomarker for immunotherapy in metastatic renal cell carcinoma.Frontiers in immunology · 2023Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the mechanism of serum interleukin-6 (IL-6) change in disease progression of interstitial nephritis.
methodsThis is a retrospective study. From November 2017 to November 2019, 87 patients with interstitial nephritis treated in our hospital were enrolled and divided into an acute group (n=42) and a chronic group (n=45) based on pathological results of renal biopsies. Forty healthy individuals after physical examination during the same period were enrolled into the reference group. Serum IL-6 levels were determined using the enzyme-linked immunosorbent assay (ELISA).
resultsAmong the three groups, patients in the acute group showed the highest IL-6 level (P<0.001). The acute group obtained higher serum advanced oxidation protein products (AOPP) levels and glomerular filtration rate (GFR) than the other two groups (P<0.05). The acute group showed lower levels of CD34
conclusionsSerum IL-6 shows a great potential as an important marker of disease progression in interstitial nephritis.
Indexed as
Identifiers
35702112PMC9185073W4285743205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.