ArticleAmerican journal of translational research2022
Expression and prognostic value of ratios of platelet lymphocyte, neutrophil lymphocyte and lymphocyte monocyte in breast cancer patients.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic value of pretreatment neutrophil-to-lymphocyte ratio in breast cancer patients receiving neoadjuvant chemotherapy: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Prognostic value of lymphocyte-to-monocyte ratio for breast cancer: a systematic review and meta-analysis.BMC women's health · 2025Pooled it
- Prognostic value of platelet to lymphocyte ratio (PLR) in breast cancer patients receiving neoadjuvant therapy: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Pooled it
- Dynamic nomogram for predicting axillary lymph node metastasis in breast cancer based on MRI analysis and the platelet-to-lymphocyte ratio (PLR).Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- A time-dependent model for quantifying postoperative inflammatory trajectories and predicting survival in early triple-negative breast cancer.World journal of surgical oncology · 2025Article
- The Evaluation of Diagnostic, Prognostic, and Predictive Role of Hematologic Inflammatory Indices NLR, PLR, and LMR in Common Solid Tumors.Cancer reports (Hoboken, N.J.) · 2025Review
- Circulating chemokines and leukocytes and their impact on breast cancer prognosis.Discover oncology · 2025Article
- Diagnostic utility of serum prostate-specific antigen and circulating inflammatory markers for differentiating prostate cancer from benign prostatic hyperplasia.American journal of cancer research · 2025Article
- The post-orchiectomy systemic inflammatory index is associated with tumor characteristics in clinical stage I germ cell tumors.Frontiers in oncology · 2025Article
- Evaluation of the Prognostic Value of Obesity, Vitamin D Concentrations, and Systemic Inflammatory Response Indexes (SIRI, SII, PIV) in Patients With Breast Cancer Scheduled for Neoadjuvant Treatment.Breast cancer : basic and clinical research · 2025Article
- Clinical characteristics and prognostic factors of male breast cancer in China.Frontiers in oncology · 2024Article
- Investigating the clinical predictive utility of inflammatory markers and nomogram development in colorectal cancer patients with malnutrition.Frontiers in nutrition · 2024Article
- Prognostic value of preoperative immune-nutritional scoring systems in remnant gastric cancer patients undergoing surgery.World journal of gastrointestinal surgery · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe ratios of systemic inflammatory cells, neutrophil lymphocyte (NLR), platelet lymphocyte (PLR) and lymphocyte monocyte (LMR) can be used as prognostic indicators of breast cancer (BC). The purpose of this study was to explore the value of inflammatory markers in predicting the pathological reaction and prognosis of patients with BC after surgical treatment.
methodsA total of 144 BC patients who received standard neoadjuvant therapy in Shangqiu First People's Hospital from January 2016 to January 2018 were analyzed retrospectively. The clinical data of patients were collected and the effects of NLR, PLR and LMR on disease-free survival were evaluated by chi-square test and COX regression. The diagnostic value of NLR, PLR and LMR in BC recurrence was analyzed by receiver operating characteristic (ROC) curve.
resultsOf the 144 patients, 20 (13.89%) had local or distant metastasis. The areas under the ROC curve of NLR, PLR and LMR in peripheral blood for the diagnosis of BC recurrence were 0.713, 0.683 and 0.765, respectively. Multivariate Cox regression analysis showed that T stage, lymph node metastasis, PLR, LMR and HER2 were independent risk factors for prognosis.
conclusionInflammatory markers based on NLR, PLR and LMR may become biological indicators to predict the pathological features and prognosis of invasive BC in the future.
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35702097PMC9185042What OpenQuestion holds
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