Evidence map›Paper›PMID 35701879›Full record

ArticleClinical anatomy (New York, N.Y.)2022

Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy.

Michelle Chua, Khalil Salame, Morsi Khashan, Dror Ofir, Uri Hochberg, Ran Ankory, Zvi Lidar, Gilad J Regev

Open access · hybridAbstract read
In one paragraph

Article in Clinical anatomy (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michelle ChuaDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Khalil SalameDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Morsi KhashanDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Dror OfirDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Uri HochbergDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Ran AnkoryDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Zvi LidarDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.
Gilad J RegevDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv.ORCID https://orcid.org/0000-0002-4079-1068
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between degenerative zygapophysial joint (facet) arthropathy and multifidus muscle atrophy has not been rigorously evaluated. The purpose of this study was to determine if specific morphological features of degenerative facet arthropathy are correlated with multifidus muscle atrophy. We retrospectively reviewed medical records and imaging studies of patients with lumbar spinal stenosis. Facet overhang, bridging osteophyte formation, facet effusion, and facet angles were evaluated by univariable and multivariable regression to identify independent associations with deep and superficial parts of the multifidus total cross-sectional area (tCSA), functional cross-sectional area (fnCSA), and fatty infiltration (FI). Facet overhang was classified as severe in 50 females (53.2%) versus 56 males (36.9%) (p = 0.030). Severity of facet overhang and female sex were independently associated with smaller deep part of the multifidus tCSA and fnCSA as well as higher FI, reflecting greater atrophy of the deep region compared to total muscle mass. In comparison, severe facet overhang (p < 0.001; OR = 3.47, 95% CI = 2.13-5.66) and female sex (p < 0.001; OR = 4.19, 95% CI = 2.58-6.79) were independently associated only with higher superficial part of the multifidus FI, reflecting muscle steatosis without significant lean muscle atrophy. In patients with degenerative lumbar spinal stenosis, facet overhang is an independent risk factor for deep part of the multifidus atrophy. Bridging osteophyte formation, facet effusion, and facet angles were not independently associated with deep part of the multifidus atrophy.

Indexed as

Joint DiseasesOsteophyteSpinal StenosisFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMaleMuscular AtrophyParaspinal MusclesRetrospective Studiescross-sectional areafacet arthropathyfatty infiltrationlumbar spinal stenosismultifidusmuscle atrophy

Identifiers

PMID35701879
PMCPMC9795881
OpenAlexW4282918553

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.