Evidence map›Paper›PMID 35701683›Full record

ArticleLa Radiologia medica2022

A comparative analysis of thermal ablation techniques in the treatment of primary and secondary lung tumors: a single-center experience.

Rosario Francesco Grasso, Caterina Bernetti, Giuseppina Pacella, Carlo Altomare, Gennaro Castiello, Flavio Andresciani, Marina Sarli, Bruno Beomonte Zobel, Eliodoro Faiella

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07398027 (Post-Market Study of Transbronchial Cryo-assisted RFA During Robotic Assisted Bronchoscopy With Subsequent Surgical Resection), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07398027 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Post-Market Study of Transbronchial Cryo-assisted RFA During Robotic Assisted Bronchoscopy With Subsequent Surgical Resection (CRONOS-CH)

TypeinterventionalSponsorCarolin SteinackRan2026 to 2027Enrolled20ConditionsLung CancerArmsHybridTherm® System
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  7. Radiomics in Lung Metastases: A Systematic Review.Journal of personalized medicine · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rosario Francesco GrassoDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy. r.grasso@policlinicocampus.it.ORCID http://orcid.org/0000-0001-8660-7070
Caterina BernettiDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.ORCID http://orcid.org/0000-0003-1511-2358
Giuseppina PacellaDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.ORCID http://orcid.org/0000-0003-4903-8715
Carlo AltomareDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.
Gennaro CastielloDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.
Flavio AndrescianiDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.
Marina SarliDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.
Bruno Beomonte ZobelDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.ORCID http://orcid.org/0000-0001-9227-5535
Eliodoro FaiellaDepartmental Faculty of Medicine and Surgery, Unit of Interventional Radiology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo, 21, 00128, Rome, Italy.ORCID http://orcid.org/0000-0002-7367-6891
Università Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) in unresectable lung malignancies.

methodsData regarding patients with primary and secondary lung tumors treated with RFA or MWA from 2008 to 2020 were reviewed retrospectively. Primary study objectives such as technical success, primary and secondary technique efficacy rates, local tumor progression (LTP) rate, LPT-free survival (LPTFS) and overall survival (OS) were assessed. Secondary study objectives were side effects and complications. RFA and MWA were compared using the Chi-square test for continuous variables. Kaplan-Meier curves were calculated for survival statistical analysis.

resultsA total of 113 patients with primary or secondary lung tumor underwent 74 RFA (48%) and 81 MWA (52%). Technical success rate was 151/155 (97%); primary and secondary technique efficacy rates were 123/155 (79%) and 129/155 (83%), respectively. During the entire study follow-up, 32 cases experienced disease progression (20%), of which 18 underwent repeat ablation (12%), in 6 cases with success (4%). Residual unablated tumor happened in 4/155 cases (3%). LTP occurred in 28/155 cases (17%). The only factor associated with poorer LTP-FS was lesion diameter ≥ 30 mm (P < 0.05). One-, 3- and 5-years LTP-FS was 83%, 82%, 82%, respectively. One-, 3- and 5-years OS of the entire population was 87%, 74%, 73%, respectively. Minor and major complication rates were 53/155 (34%) and 29/155 (19%), respectively.

conclusionsIn conclusion, this study confirms the appropriateness of RFA and MWA for lung tumors treatment, in terms of safety and efficacy.

Indexed as

Ablation TechniquesCatheter AblationLiver NeoplasmsLung NeoplasmsHumansMicrowavesRetrospective StudiesTreatment OutcomeLung metastasisLung tumorsMicrowave ablationRadiofrequency ablationSIRIO

Identifiers

PMID35701683
OpenAlexW4282829272

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.