Evidence map›Paper›PMID 35701677›Full record

ReviewTopics in current chemistry (Cham)2022

Metal Peptide Conjugates in Cell and Tissue Imaging and Biosensing.

Karmel S Gkika, David Cullinane, Tia E Keyes

Abstract readReview
In one paragraph

Review in Topics in current chemistry (Cham), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Liposomal Delivery of Cell Impermeable Phototoxic Ru(II) Complexes.Chembiochem : a European journal of chemical biology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karmel S GkikaSchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland.
David CullinaneSchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland.
Tia E KeyesSchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland. tia.keyes@dcu.ie.ORCID http://orcid.org/0000-0002-4604-5533

Funding

Science Foundation Ireland [12/RC/2276_P2]Science Foundation Ireland [19/FFP/6428]
6 · The paper itself

Abstract

Metal complex luminophores have seen dramatic expansion in application as imaging probes over the past decade. This has been enabled by growing understanding of methods to promote their cell permeation and intracellular targeting. Amongst the successful approaches that have been applied in this regard is peptide-facilitated delivery. Cell-permeating or signal peptides can be readily conjugated to metal complex luminophores and have shown excellent response in carrying such cargo through the cell membrane. In this article, we describe the rationale behind applying metal complexes as probes and sensors in cell imaging and outline the advantages to be gained by applying peptides as the carrier for complex luminophores. We describe some of the progress that has been made in applying peptides in metal complex peptide-driven conjugates as a strategy for cell permeation and targeting of transition metal luminophores. Finally, we provide key examples of their application and outline areas for future progress.

Indexed as

Coordination ComplexesPeptidesBiosensing TechniquesCoordination ComplexesPeptidesCell-penetrating peptidesImagingMetal conjugatesMPPOctaargininePeptidePhotophysicsSignal peptidesTransition metal luminophores

Identifiers

PMID35701677
PMCPMC9197911

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.