ReviewNatural products and bioprospecting2022
Chemistry and bioactivities of natural steroidal alkaloids.
Review in Natural products and bioprospecting, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Design, Synthesis, and Biological Evaluation of N-Acyl Pregnane Alkaloid Ester Derivatives as Acetylcholinesterase and α-Glucosidase Inhibitors.Chemistry & biodiversity · 2026Article
- Solasodine, a Natural Steroidal Alkaloid, Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption: A Study Based on Network Pharmacology and Experimental Validation.Journal of cellular and molecular medicine · 2026Article
- In silico prediction, molecular docking, and dynamics analysis of steroidal alkaloids from the genus Fritillaria: implications for designing novel antiparkinsonian therapeutic strategies.Scientific reports · 2026Article
- Natural Alkaloids as Antimicrobial Agents: Mechanisms, Potentials and Challenges.Molecules (Basel, Switzerland) · 2026Review
- Untargeted metabolomics reveals key steroidal glycoalkaloids and associated metabolites in crude and C18-purified extracts of potato leaves.BMC plant biology · 2026Article
- Integrated metabolomics and transcriptomics investigate the bulb-specific biosynthesis of medicinal steroidal alkaloids in Fritillaria taipaiensis.BMC plant biology · 2026Article
- Mechanisms of Traditional Chinese Medicine-Derived Alkaloids in Colorectal Cancer Therapy: Molecular Targets, Preclinical Evidence, and Translational Prospects.Drug design, development and therapy · 2026Review
- Article
- Solasodine inhibited the proliferation of gastric cancer cells through suppression of Hedgehog/Gli1 signaling.Food science and biotechnology · 2025Article
- Seasonal, Organ-, and Location-Dependent Variations in the Alkaloid Content ofPlants (Basel, Switzerland) · 2025Article
- Comparative metabolomics reveals how the severity of predation by the invasive insect Cydalima perspectalis modulates the metabolism re-orchestration of native Buxus sempervirens.Plant biology (Stuttgart, Germany) · 2025Article
- Review
- Antiprotozoal Aminosteroids fromMolecules (Basel, Switzerland) · 2025Article
- Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature's secrets in forensic science.Natural products and bioprospecting · 2025Review
- Pulmonary hypertension: etiology and anti-inflammatory treatment pathways of natural products.Frontiers in pharmacology · 2025Review
- Review
- Verazine biosynthesis from simple sugars in engineered Saccharomyces cerevisiae.Metabolic engineering · 2024Article
- Investigating Changes in Pharmacokinetics of Steroidal Alkaloids from a HydroethanolicPharmaceuticals (Basel, Switzerland) · 2024Article
- Divergent and gram-scale syntheses of (-)-veratramine and (-)-cyclopamine.Nature communications · 2024Article
- Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery.Natural products and bioprospecting · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Steroidal alkaloids possess the basic steroidal skeleton with a nitrogen atom in rings or side chains incorporated as an integral part of the molecule. They have demonstrated a wide range of biological activities, and some of them have even been developed as therapeutic drugs, such as abiraterone acetate (Zytiga
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.