Evidence map›Paper›PMID 35701628›Full record

ArticleClinical rheumatology2022

COVID-19 quarantine in adolescents with autoimmune rheumatic diseases: mental health issues and life conditions.

Bianca P Ihara, Lívia M Lindoso, Debora N D Setoue, Nicolas Y Tanigava, Alberto C Helito, Juliana R Simon, Vivianne S L Viana, Claudia A A Strabelli, Camilla A A Pedroso, Sofia M Sieczkowska and 11 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Bianca P IharaInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil. bia.ihara@gmail.com.ORCID http://orcid.org/0000-0002-2628-8060
Lívia M LindosoInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3452-8789
Debora N D SetoueInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7077-3867
Nicolas Y TanigavaRheumatology Division, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2096-2042
Alberto C HelitoInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0673-0413
Juliana R SimonInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3775-8822
Vivianne S L VianaInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0660-4142
Claudia A A StrabelliInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7940-7345
Camilla A A PedrosoRheumatology Division, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4033-2432
Sofia M SieczkowskaRheumatology Division, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-4869-318X
Rosa M R PereiraRheumatology Division, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3723-5028
Nádia E AikawaInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7585-4348
Katia T KozuInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8743-7827
Adriana M EliasInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0823-6459
Izabel M BuscattiInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9140-8823
Bruno GualanoRheumatology Division, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7100-8681
Ligia B QueirozInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0326-7072
Caio B CasellaInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-2048-5909
Guilherme V PolanczykDepartment of Psychiatry, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-2311-3289
Clovis A A SilvaInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9250-6508
Lucia M M A CamposInstituto da Criança E Do Adolescente, Hospital das Clínicas HCFMUSP, University of São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9653-0468
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 305242/2019-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/03756-4
6 · The paper itself

Abstract

objectivesTo assess mental health and life conditions in adolescents with autoimmune rheumatic diseases (ARDs) and healthy controls quarantined during COVID-19 pandemic.

methodA cross-sectional study included 155 ARD adolescents and 105 healthy controls. Online survey included self-reported strengths and difficulties questionnaire (SDQ), and a semi-structured questionnaire with demographic data, daily home and school routine, physical activities, and COVID-19 information during the pandemic.

resultsAmong patients, 56% had juvenile idiopathic arthritis (JIA), 29% juvenile systemic lupus erythematosus (JSLE), and 15% juvenile dermatomyositis (JDM). No differences were found regarding sex, ethnicity, and current age between ARD patients and controls (p > 0.05). Abnormal emotional SDQ (38% vs. 35%, p = 0.653) were similar in both groups. Logistic regression analyses in ARD patients demonstrated that female (OR = 2.4; 95%CI 1.0-6.0; p = 0.044) was associated with severe emotional SDQ dysfunction, whereas sleep problems were considered as a risk factor for both worse total SDQ (OR = 2.6; 95%CI 1.2-5.5; p = 0.009) and emotional SDQ scores (OR = 4.6; 95%CI 2.2-9.7; p < 0.001). Comparisons between ARD patients with and without current prednisone use showed higher median scores of peer problems in the first group [3 (0-10) vs. 2 (0-7), p = 0.049], whereas similar median and frequencies between JIA, JSLE, and JDM (p > 0.05).

conclusionsApproximately one third of JIA, JSLE, and JDM patients presented abnormal total and emotional scores of SDQ during COVID-19 quarantine. Sleep problems were the main factor associated with emotional difficulties in these ARD adolescents. The knowledge of mental health issues rates in adolescents with ARD supports the development of prevention strategies, like sleep hygiene counseling, as well as the references of the affected patients to specialized mental health services, as necessary. Key Points • One third of ARD patients presented mental health issues during COVID-19 quarantine • Sleep problems were associated with emotional difficulties. • It is necessary to warn pediatric rheumatologists about the importance of sleep hygiene counseling.

Indexed as

Arthritis, JuvenileCOVID-19DermatomyositisLupus Erythematosus, SystemicSleep Wake DisordersAdolescentChildCross-Sectional StudiesFemaleHumansMental HealthPandemicsPrednisoneQuarantinePrednisoneAutoimmune rheumatic diseasesCOVID-19Life conditionsMental health issues

Identifiers

PMID35701628
PMCPMC9197675
OpenAlexW4282918641

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.