Evidence map›Paper›PMID 35701552›Full record

ArticleClinical oral investigations2022

Malocclusion complexity and orthodontic treatment need in children with autism spectrum disorder.

Stephanie A Meuffels, Anne Marie Kuijpers-Jagtman, Stephen T H Tjoa, Clarissa C Bonifacio, Paola L Carvajal Monroy

Abstract read
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Orthodontic aligner therapy outcomes in children with autism spectrum disorder.International journal of paediatric dentistry · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie A MeuffelsDepartment of Pediatric Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands.
Anne Marie Kuijpers-JagtmanDepartment of Orthodontics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Stephen T H TjoaDepartment of Oral and Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus Medical Center, Rotterdam, the Netherlands.
Clarissa C BonifacioDepartment of Pediatric Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands.
Paola L Carvajal MonroyDepartment of Oral and Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus Medical Center, Rotterdam, the Netherlands. p.carvajalmonroy@erasmusmc.nl.ORCID http://orcid.org/0000-0003-2391-7308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to investigate the malocclusion complexity and orthodontic treatment need among children with and without autism spectrum disorder (ASD) referred for orthodontic treatment by quantifying the Discrepancy Index (DI) and Index of Orthodontic Treatment Need (IOTN). MATERIALS AND

methodsDental records of 48 ASD and 49 non-ASD consecutive patients aged between 9 and 18 years (median age 13.0 years) referred for orthodontic treatment were reviewed and compared. The Discrepancy Index (DI) was quantified to determine the malocclusion complexity, and the Index of Orthodontic Treatment Need (IOTN), including the Dental Health Component (IOTN-DHC) and Aesthetic Component (IOTN-AC), was quantified to determine the orthodontic treatment need. Statistical analysis included descriptive analysis, Pearson chi-square tests, Fisher's exact test, Mann-Whitney U tests, and several univariate and multivariate regression analyses. The statistical analysis used descriptive analysis, Pearson chi-square test, Fisher's exact test, and multivariate logistic regression.

resultsThe results show that both malocclusion complexity (DI, p = 0.0010) and orthodontic treatment need (IOTN-DHC, p = 0.0025; IOTN-AC p = 0.0009) were significantly higher in children with ASD. Furthermore, children with ASD had a higher prevalence of increased overjet (p = .0016) and overbite (p = .031).

conclusionsMalocclusion complexity and orthodontic treatment need are statistically significantly higher among children with ASD than children without ASD, independent of age and sex. CLINICAL RELEVANCE: Children with autism may benefit from visits to a dental specialist (orthodontist) to prevent, to some extent, developing malocclusions from an early age.

Indexed as

Autism Spectrum DisorderMalocclusionMalocclusion, Angle Class IIOverbiteAdolescentChildEsthetics, DentalHealth Services Needs and DemandHumansIndex of Orthodontic Treatment NeedOrthodontics, CorrectiveAdolescentAutism spectrum disorderChildIndex of Orthodontic Treatment NeedMalocclusionNeeds assessmentOrthodontic care

Identifiers

PMID35701552
PMCPMC9525343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.